Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712795 | 0.89 | L3MBTL1 (0.36) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL439265 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL9883735 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL16692642 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRSLC22A6AKR1B1 | |
| SCHEMBL21896383 | 0.84 | HMGCR (0.37) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL1781906 | 0.82 | BLM (0.34) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL12227935 | 0.82 | ALDH1A1 (0.36) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL19646421 | 0.81 | MEN1 (0.38) | TSHR | |
| SCHEMBL23935415 | 0.80 | ALDH1A1 (0.33) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL10911455 | 0.80 | NAALAD2 (0.34) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013000970-A1 | BIS TRIDENTATE W3O2 CLUSTERS FOR X-RAY IMAGING | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-03 | — | — | WO | claimed |
| EP-2540321-A1 | Bis Tridentate W3O2 Clusters for X-Ray imaging | Bayer Intellectual Property GmbH (DE) | 2013-01-02 | — | — | EP | claimed |
| US-9714421-B2 | Compositions and methods | IONIS PHARMACEUTICALS, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-20170183661-A1 | COMPOSITIONS AND METHODS FOR MODULATING PKK EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2017-06-29 | — | — | US | disclosed |
| US-20170166899-A1 | COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2017-06-15 | — | — | US | disclosed |
| US-20170159055-A1 | COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2017-06-08 | — | — | US | disclosed |
| US-9671396-B2 | Solid substrate comprising array of dendrons and methods for using the same | PARK JOON WON (KR) | 2017-06-06 | — | — | US | disclosed |
| US-20170145424-A1 | COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS | IONIS PHARMACEUTICALS, INC. (US) | 2017-05-25 | — | — | US | disclosed |
| US-9389227-B2 | Solid substrate comprising array of dendrons and methods for using the same | POSCO (KR) | 2016-07-12 | — | — | US | disclosed |
| US-20160194349-A1 | COMPOSITIONS AND METHODS FOR MODULATING ANGIOPOIETIN-LIKE 3 EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2016-07-07 | — | — | US | disclosed |
| US-9382540-B2 | Compositions and methods for modulating angiopoietin-like 3 expression | ISIS PHARMACEUTICALS, INC (US) | 2016-07-05 | — | — | US | disclosed |
| US-20120136042-A1 | CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC (US) | 2012-05-31 | — | — | US | disclosed |
| US-8106022-B2 | Carbohydrate conjugates as delivery agents for oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-20080274915-A1 | Solid Substrate Comprising Array of Dendrons and Methods for Using the Same | PARK JOON WON | 2008-11-06 | — | — | US | disclosed |
| US-20080113353-A1 | Cantilevers with fixed end and free end modified by dendron | POSTECH FOUNDATION (KR) | 2008-05-15 | — | — | US | disclosed |
| US-20080064070-A1 | POLYNUCLEOTIDE SYNTHESIS ON A MODIFIED SURFACE | POSTECH FOUNDATION (KR) | 2008-03-13 | — | — | US | disclosed |
| US-20070128623-A1 | Cantilevers with fixed end and free end modified by dendron | POSTECH FOUNDATION (KR) | 2007-06-07 | — | — | US | disclosed |
| EP-0573848-B1 | Bile-acid derivatives, a process for their production and their use as medicines | HOECHST AG (DE) | 1997-12-03 | — | — | EP | disclosed |
| US-5428182-A | Hypolipidemic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0573848-A2 | Bile-acid derivatives, a process for their production and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145424-A1 | COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS | SI, FABP2, GNE | ALDH1A1 2760/4885LMNA 703/4885EGLN1 1750/4885 |
| US-20160194349-A1 | COMPOSITIONS AND METHODS FOR MODULATING ANGIOPOIETIN-LIKE 3 EXPRESSION | TEK, PLIN3, FABP3 | ALDH1A1 2808/4885LMNA 930/4885EGLN1 79/4885 |
| US-20120136042-A1 | CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES | LPXN, ZYX, OSTC | ALDH1A1 4231/4885LMNA 266/4885EGLN1 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.