Taurochenodeoxycholate

Taurochenodeoxycholate

SCHEMBL40763

C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 12/20 1.00
NR1H4 Q96RI1 6/20 1.00
SLC10A2 Q12908 3/20 1.00
ABCC4 O15439 2/20 1.00
ABCB11 O95342 2/20 1.00
ENPP2 Q13822 2/20 1.00
PLA2G1B P04054 1/20 1.00
SLC10A1 Q14973 6/20 0.89
VDR P11473 1/20 0.79
NR3C1 P04150 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taurochenodeoxycholate SCHEMBL9152921 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL4411471 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL13094131 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL12917602 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL24001493 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL24435723 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL17641266 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL24015433 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL17309129 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL19360984 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4618 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260131089-A1 DRUG DELIVERY DEVICES AND METHODS FOR ADMINISTERING SUBSTANCES TO A BODY CAVITY BY HETEROGENOUS AEROSOLIZATION FOR TREATMENT OF BINGE-EATING DISORDERS AND/OR OBESITY APTARGROUP, INC. (US) 2026-05-14 US claimed
US-12594388-B2 Device to deliver a predetermined amount of a substance to a natural orifice of the body APTARGROUP, INC. (US) 2026-04-07 US claimed
US-12491325-B2 Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization for treatment of binge-eating disorders and/or obesity APTARGROUP, INC. (US) 2025-12-09 US claimed
US-20250302824-A1 IN SITU READY-TO-USE INJECTION FORMULATIONS OF POSACONAZOLE FREE OF CYCLODEXTRIN AND ITS DERIVATIVES Hefei Cosource Pharmaceuticals Co., Ltd (CN) 2025-10-02 US claimed
US-12370237-B2 Lipopeptides for use in treating liver diseases and cardiovascular diseases RUPRECHT - KARLS - UNIVERSITÄT HEIDELBERG (DE) 2025-07-29 US claimed
US-20250235641-A1 DEVICE TO DELIVER A PREDETERMINED AMOUNT OF A SUBSTANCE TO A NATURAL ORIFICE OF THE BODY APTARGROUP INC. (US) 2025-07-24 US claimed
CN-119935994-A Method for identifying bear gall powder by biological enzyme method and kit thereof 江西邦泰绿色生物合成生态产业园发展有限公司 2025-05-06 CN claimed
CN-119688859-A Exhaled breath condensate metabolite combination, kit and method for predicting invasive lung adenocarcinoma 华中科技大学同济医学院附属协和医院 2025-03-25 CN claimed
CN-118903151-A Application of tauroursodeoxycholate in preparing COL4A3 gene mutation kidney injury treatment medicine 上海交通大学医学院附属瑞金医院 2024-11-08 CN claimed
CN-118680941-A Use of sodium phenylbutyrate and tauroursodeoxycholate in combination for preventing, improving or treating cognitive disorder 重庆医科大学 2024-09-24 CN claimed
US-5352460-A Blending powders of bile salt, buffer, adhesive polymer, disintegrant, wetting, granulating or extruding, compacting uniform particles to spheres, drying, sorting, coating with acid resistant polymer, drying DIGESTIVE CARE INC. (US) 1994-10-04 US claimed
US-5324514-A Digestive system disorders DIGESTIVE CARE INC. (US) 1994-06-28 US claimed
US-5302400-A Blending pulverized enzymes and buffers, compacting, drying, coating with acid-resistant polymer DIGESTIVE CARE INC. (US) 1994-04-12 US claimed
EP-0576938-A1 Composition of digestive enzymes and salts of bile acids and process for preparation thereof DIGESTIVE CARE INC. (US) 1994-01-05 EP claimed
EP-0574894-A1 Composition of gastric acid - resistant microspheres containing buffered bile acids DIGESTIVE CARE INC. (US) 1993-12-22 EP claimed
US-5262172-A Microencapsulation with carbonate, bicarbonate and amine buffers DIGESTIVE CARE INC. (US) 1993-11-16 US claimed
US-5260074-A Compositions of digestive enzymes and salts of bile acids and process for preparation thereof DIGESTIVE CARE INC. (US) 1993-11-09 US claimed
EP-0551451-A1 N-ALKYL-TAUROURSODEOXYCHOLIC ACIDS AND THEIR THERAPEUTICALLY ACTIVE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PRODOTTI CHIMICI E ALIMENTARI SPA (IT) 1993-07-21 EP claimed
EP-0513887-A1 N-alkyltauroursodeoxycholic acids and their therapeutically active derivatives, a process for their preparation and pharmaceutical compositions containing them PRODOTTI CHIMICI E ALIMENTARI SPA (IT) 1992-11-19 EP claimed
WO-1992018524-A1 N-ALKYL-TAUROURSODEOXYCHOLIC ACIDS AND THEIR THERAPEUTICALLY ACTIVE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PRODOTTI CHIMICI E ALIMENTARI S.P.A. (IT) 1992-10-29 WO claimed