Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 2/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206292 | 0.74 | KMT2A (0.42) | C3AR1PYGLMEN1KMT2AKDM4E | |
| SCHEMBL2984799 | 0.72 | TDP1 (0.44) | AVPR1AOXTR | |
| SCHEMBL2976914 | 0.72 | TSHR (0.49) | AVPR1ATSHR | |
| SCHEMBL2991416 | 0.70 | AVPR1A (0.41) | AVPR1AOXTR | |
| SCHEMBL4861833 | 0.69 | MEN1 (0.46) | CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL206987 | 0.68 | POLB (0.56) | CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL207560 | 0.68 | POLB (0.41) | AVPR1AMEN1KMT2A | |
| SCHEMBL2979024 | 0.68 | LMNA (0.49) | AVPR1ATSHRMEN1KMT2A | |
| SCHEMBL4079453 | 0.67 | LMNA (0.43) | AVPR1ATSHROXTR | |
| SCHEMBL205911 | 0.66 | ALDH1A1 (0.40) | TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |