Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | RBP4 | P02753 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4482591 | 0.86 | MEN1 (0.45) | SLC6A2SLC6A4MEN1KMT2ANPSR1 | |
| SCHEMBL4078049 | 0.74 | SLC6A2 (0.49) | SLC6A2SLC6A4KDM4EOPRK1ALDH1A1 | |
| SCHEMBL13708241 | 0.74 | SLC6A2 (0.49) | SLC6A2SLC6A4KDM4EOPRK1ALDH1A1 | |
| SCHEMBL4070662 | 0.73 | KDM1A (0.40) | KDM4EGAAATMMAPT | |
| SCHEMBL4934342 | 0.72 | ALDH1A1 (0.40) | KDM4EALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL4941691 | 0.72 | ALDH1A1 (0.40) | KDM4EALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL4934346 | 0.72 | ALDH1A1 (0.40) | KDM4EALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL4933481 | 0.72 | ALDH1A1 (0.40) | KDM4EALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL4940955 | 0.72 | ALDH1A1 (0.40) | KDM4EALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL4080093 | 0.72 | GPR119 (0.36) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716126-B1 | MORPHOLINE DERIVATIVES AS NOREPINEPHRINE REUPTAKE INHIBITORS | LILLY CO ELI (US) | 2009-02-25 | — | — | EP | disclosed |