Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94614 | 0.81 | SMN1; SMN2 (0.41) | BRPF1SMN1; SMN2HSD17B3GAAMEN1 | |
| SCHEMBL5458675 | 0.73 | BRPF1 (0.40) | BRPF1SMN1; SMN2HSD17B3GAAMEN1 | |
| SCHEMBL8039565 | 0.72 | BRPF1 (0.39) | BRPF1SMN1; SMN2HSD17B3GAAMEN1 | |
| SCHEMBL6648901 | 0.72 | EPHX2 (0.51) | SMN1; SMN2GAAMEN1KMT2AKDM4E | |
| SCHEMBL27725668 | 0.69 | SMN1; SMN2 (0.36) | SMN1; SMN2HSD17B3GAAMEN1KMT2A | |
| SCHEMBL9521938 | 0.68 | BRPF1 (0.41) | BRPF1SMN1; SMN2HSD17B3GAAMEN1 | |
| SCHEMBL17114712 | 0.68 | BRPF1 (0.41) | BRPF1SMN1; SMN2HSD17B3GAAMEN1 | |
| SCHEMBL8304937 | 0.68 | BRPF1 (0.41) | BRPF1SMN1; SMN2HSD17B3GAAMEN1 | |
| SCHEMBL21400260 | 0.68 | BRPF1 (0.41) | BRPF1SMN1; SMN2HSD17B3GAAMEN1 | |
| SCHEMBL4265285 | 0.68 | BRPF1 (0.41) | BRPF1SMN1; SMN2HSD17B3GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009039321-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-03-26 | — | — | WO | disclosed |
| CN-1703259-A | Heterocyclic compound for stimulating or inducing hair or eyelash growth and/or for slowing down hair loss, composition containing same, and uses thereof | OREAL (FR) | 2005-11-30 | — | — | CN | disclosed |
| US-4035395-A | Process for the preparation of ketones | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | disclosed |
| US-4014889-A | Process for preparing ketones | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |