Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 7/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL9443644 | 0.92 | APP (0.41) | APPCYP3A4ALDH1A1GFERTSHR | |
| Aniline SCHEMBL29187472 | 0.87 | MAOB (0.50) | ALDH1A1TSHRMAOBMAOAGAA | |
| Aniline SCHEMBL29187471 | 0.87 | MAOB (0.50) | ALDH1A1TSHRMAOBMAOAGAA | |
| SCHEMBL28119658 | 0.85 | ABAT (0.48) | MAOBLOXL2CA6CA14CA2 | |
| SCHEMBL22589820 | 0.84 | IDO1 (0.48) | APPALDH1A1TDP1L3MBTL1IDO1 | |
| SCHEMBL9849124 | 0.83 | TAAR1 (0.54) | ALDH1A1TSHRTDP1MAOBLOXL2 | |
| SCHEMBL17061043 | 0.83 | CYP3A4 (0.50) | APPCYP3A4IDO1 | |
| SCHEMBL3365610 | 0.83 | PRSS1 (0.39) | APPALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL742829 | 0.82 | ALDH1A1 (0.46) | APPCYP3A4ALDH1A1GFERTSHR | |
| SCHEMBL4055238 | 0.81 | IDO1 (0.48) | APPMAOBIDO1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118339172-A | Phosphonic acid compounds and prodrugs thereof, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-11801315-B2 | Radioligands for myelin | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-10-31 | — | — | US | disclosed |
| US-20230201382-A1 | RADIOLIGANDS FOR MYELIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-06-29 | — | — | US | disclosed |
| EP-3426309-B1 | RADIOLIGANDS FOR MYELIN | UNIV CASE WESTERN RESERVE (US) | 2022-05-04 | — | — | EP | disclosed |
| CN-113677350-A | ENPP1 inhibitors and methods of modulating immune responses | 里兰斯坦福初级大学理事会 | 2021-11-19 | — | — | CN | disclosed |
| US-20210128756-A1 | RADIOLIGANDS FOR MYELIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-05-06 | — | — | US | disclosed |
| US-10765763-B2 | Radioligands for myelin | CASE WESTERN RESERVE UNIVERSITY (US) | 2020-09-08 | — | — | US | disclosed |
| US-20190134232-A1 | RADIOLIGANDS FOR MYELIN | CASE WESTERN RESERVE UNIVERSITY | 2019-05-09 | — | — | US | disclosed |
| EP-3426309-A1 | RADIOLIGANDS FOR MYELIN | Case Western Reserve University (US) | 2019-01-16 | — | — | EP | disclosed |
| WO-2017156303-A1 | RADIOLIGANDS FOR MYELIN | CASE WESTERN RESERVE UNIVERSITY (US) | 2017-09-14 | — | — | WO | disclosed |
| US-20050128562-A1 | Nanoporous and nanocrystalline film and electrochromic device | UNIVERSITY COLLEGE DUBLIN, A CONSTITUENT COLLEGE OF THE NATIONAL UNIVERSITY OF IRELAND | 2005-06-16 | — | — | US | disclosed |
| US-20050128561-A1 | Electrochromic compound | UNIVERSITY COLLEGE DUBLIN, A CONSTITUENT COLLEGE OF THE NATIONAL UNIVERSITY OF IRELAND | 2005-06-16 | — | — | US | disclosed |
| US-6870657-B1 | Electrochromic device | UNIVERSITY COLLEGE DUBLIN (IE) | 2005-03-22 | — | — | US | disclosed |
| EP-1500969-A1 | Compound and its use in electrochromic devices | UNIVERSITY COLLEGE DUBLIN (IE) | 2005-01-26 | — | — | EP | disclosed |
| EP-1224505-B1 | ELECTROCHROMIC DEVICE | UNIV DUBLIN (IE) | 2005-01-12 | — | — | EP | disclosed |
| WO-2004100960-A2 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2004-11-25 | — | — | WO | disclosed |
| WO-2004096236-A2 | IMMUNOMODULATOR PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | disclosed |
| EP-1224505-A1 | ELECTROCHROMIC DEVICE | UNIVERSITY COLLEGE DUBLIN (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001027690-A2 | ELECTROCHROMIC DEVICE | UNIVERSITY COLLEGE DUBLIN (IE) | 2001-04-19 | — | — | WO | disclosed |
| WO-1990008185-A1 | MOLECULES WITH ANTIBODY COMBINING SITES THAT EXHIBIT STEREOSPECIFIC CATALYSIS | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1990-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190134232-A1 | RADIOLIGANDS FOR MYELIN | MAG, PMP22, MYT1 | APP 1224/4885CYP3A4 4569/4885ALDH1A1 3084/4885 |
| US-20230201382-A1 | RADIOLIGANDS FOR MYELIN | MAG, PMP22, MYT1 | APP 1514/4885CYP3A4 2877/4885ALDH1A1 2144/4885 |
| US-20210128756-A1 | RADIOLIGANDS FOR MYELIN | MAG, PMP22, MYT1 | APP 1224/4885CYP3A4 4569/4885ALDH1A1 3084/4885 |
| US-11801315-B2 | Radioligands for myelin | MAG, PMP22, MYT1 | APP 1224/4885CYP3A4 4569/4885ALDH1A1 3084/4885 |
| US-10765763-B2 | Radioligands for myelin | MAG, PMP22, MYT1 | APP 1224/4885CYP3A4 4569/4885ALDH1A1 3084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.