SCHEMBL742829

SCHEMBL742829

Nc1ccc(CO[PH](=O)OCc2ccc(N)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
CYP3A4 P08684 2/20 0.46
GFER P55789 1/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.44
MAOB P27338 9/20 0.44
APP P05067 1/20 0.44
MAOA P21397 3/20 0.42
MAPT P10636 2/20 0.42
GAA P10253 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
RECQL P46063 1/20 0.38
FDPS P14324 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9849123 0.82 TAAR1 (0.52) ALDH1A1TSHRTDP1LOXL2MAOB
SCHEMBL2637292 0.82 TSHR (0.42) ALDH1A1CYP3A4GFERTSHRTDP1
SCHEMBL4076437 0.82 APP (0.46) ALDH1A1CYP3A4GFERTSHRTDP1
SCHEMBL8855401 0.81 IDO1 (0.50) ALDH1A1TDP1APPL3MBTL1MEN1
SCHEMBL5432093 0.79 AGXT (0.52) ALDH1A1MAOBMAOAMAPTRAB9A
SCHEMBL17061042 0.79 CYP3A4 (0.52) CYP3A4APP
SCHEMBL9849327 0.79 TRPA1 (0.39) ALDH1A1TSHRCA2CA9
SCHEMBL6020749 0.79 CA2 (0.32) CA2CA9
SCHEMBL4055235 0.79 IDO1 (0.52) LOXL2MAOBAPPCA2CA9
SCHEMBL2016123 0.79 IDO1 (0.52) MAOBAPPMAOAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119136615-A Perovskite light absorption layer, method for improving crystallization and carrier transmission of perovskite light absorption layer simultaneously and application 仁烁光能(苏州)有限公司 2024-12-13 CN claimed
EP-0123300-A2 Complexing of biologically active or functional compounds and methods of preparing and utilizing same ENZO BIOCHEM, INC. (US) 1984-10-31 EP claimed
US-4230618-A CELLULOSE ICI UNITED STATES, INC. (US) 1980-10-28 US claimed
CN-120484015-A Pigment modifier for aqueous system and application thereof 上海连泓颜料有限公司 2025-08-15 CN disclosed
CN-119136615-A Perovskite light absorption layer, method for improving crystallization and carrier transmission of perovskite light absorption layer simultaneously and application 仁烁光能(苏州)有限公司 2024-12-13 CN disclosed
CN-118843724-A Ceramic continuous fiber, method for producing same, and ceramic matrix composite material comprising same 东曹株式会社 2024-10-25 CN disclosed
CN-118339172-A Phosphonic acid compounds and prodrugs thereof, preparation method and application thereof 上海海和药物研究开发股份有限公司 2024-07-12 CN disclosed
CN-117117191-A Positive electrode lithium supplementing material, preparation method thereof, positive electrode plate and secondary battery 深圳市德方创域新能源科技有限公司 2023-11-24 CN disclosed
EP-3873867-B1 MASONRY COMPOSITIONS COMPRISING CHEMICALLY TREATED CARBON PIGMENTS CABOT CORP (US) 2023-11-22 EP disclosed
CN-116986851-A Masonry composition comprising chemically treated carbon pigments 卡博特公司 2023-11-03 CN disclosed
US-11801315-B2 Radioligands for myelin CASE WESTERN RESERVE UNIVERSITY (US) 2023-10-31 US disclosed
US-5153166-A Bonding nucleophilic ligands to polyhydroxylated material TRUSTEES OF AT BIOCHEM (US) 1992-10-06 US disclosed
WO-1990008185-A1 MOLECULES WITH ANTIBODY COMBINING SITES THAT EXHIBIT STEREOSPECIFIC CATALYSIS SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1990-07-26 WO disclosed
EP-0356838-A2 Chromatographic stationary supports AT BIOCHEM (US) 1990-03-07 EP disclosed
EP-0123300-A2 Complexing of biologically active or functional compounds and methods of preparing and utilizing same ENZO BIOCHEM, INC. (US) 1984-10-31 EP disclosed
US-4472308-A Azo dyestuffs containing an amino or acylated amino naphthol monosulfonic acid radical and at least one reactive phosphoric or phosphonic acid group ICI UNITED STATES, INC. (US) 1984-09-18 US disclosed
US-4230618-A CELLULOSE ICI UNITED STATES, INC. (US) 1980-10-28 US disclosed
US-4225491-A REACTIVE DYES FOR COTTON ICI UNITED STATES, INC. (US) 1980-09-30 US disclosed
US-4150020-A MONOAZO DYES BURLINGTON INDUSTRIES, INC. (US) 1979-04-17 US disclosed
US-4134722-A Reactive dyeing system using phosphorus acid dyes with a cyanamide compound BURLINGTON INDUSTRIES, INC. (US) 1979-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11801315-B2 Radioligands for myelin MAG, PMP22, MYT1 ALDH1A1 3084/4885CYP3A4 4569/4885GFER 2360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.