Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024389 | 0.91 | LMNA (0.56) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL4076477 | 0.91 | LMNA (0.56) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL27964844 | 0.91 | ALDH1A1 (0.44) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL19464195 | 0.85 | LMNA (0.48) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL457573 | 0.85 | LMNA (0.48) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL7108549 | 0.82 | CNR1 (0.62) | MAPTALDH1A1 | |
| SCHEMBL9063918 | 0.82 | OPRM1 (0.42) | LMNASPHK1OPRM1 | |
| SCHEMBL25953784 | 0.82 | OPRM1 (0.42) | LMNASPHK1OPRM1 | |
| SCHEMBL8468112 | 0.81 | ALDH1A1 (0.48) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL4230501 | 0.81 | TSHR (0.33) | LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968916-B1 | Process for the separation of optical isomers of the corey lactone | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 2012-07-11 | — | — | EP | claimed |
| EP-1968916-B1 | Process for the separation of optical isomers of the corey lactone | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 2012-07-11 | — | — | EP | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |