Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375041 | 0.71 | HPGD (0.53) | ALDH1A1HTTHPGDLMNAKDM4E | |
| SCHEMBL10117106 | 0.71 | KMT2A (0.49) | ALDH1A1HTTHPGDLMNATSHR | |
| SCHEMBL10279067 | 0.69 | LMNA (0.43) | ALDH1A1HTTHPGDLMNAKDM4E | |
| SCHEMBL728983 | 0.69 | GAA (0.55) | ALDH1A1LMNATSHRPOLB | |
| SCHEMBL24696326 | 0.68 | TSHR (0.57) | ALDH1A1HTTHPGDKDM4ETSHR | |
| SCHEMBL10495305 | 0.68 | HTT (0.41) | HTTHPGDLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL13624736 | 0.68 | TSHR (0.41) | ALDH1A1HTTHPGDTSHR | |
| SCHEMBL16157270 | 0.68 | KMT2A (0.41) | HTTHPGDLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL15728763 | 0.68 | KEAP1 (0.53) | LMNAKDM4ERAB9A | |
| SCHEMBL3093204 | 0.68 | CYP1A2 (0.42) | HTTHPGDLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108534-A1 | Dihydrothienopyrimidines for the treatment of inflammatory Diseases | POUZET PASCALE (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108534-A1 | Dihydrothienopyrimidines for the treatment of inflammatory Diseases | DPYD, DHFR, TPMT | ALDH1A1 302/4885HTT 1162/4885HPGD 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.