Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827479 | 0.65 | BACE1 (0.43) | BACE1BACE2CYP2C9KMT2ALMNA | |
| SCHEMBL7635908 | 0.62 | CFTR (0.56) | CYP2C9KMT2ALMNABLMPMP22 | |
| SCHEMBL11469864 | 0.61 | CFTR (0.39) | BACE1BACE2CYP2C9KMT2ALMNA | |
| SCHEMBL9304904 | 0.61 | CFTR (0.54) | CYP2C9KMT2ALMNABLMPMP22 | |
| SCHEMBL9823653 | 0.61 | BACE1 (0.39) | BACE1BACE2CYP2C9KMT2ALMNA | |
| SCHEMBL9482559 | 0.61 | BACE1 (0.39) | BACE1BACE2CYP2C9KMT2ALMNA | |
| SCHEMBL4397735 | 0.60 | CFTR (0.34) | BACE1BACE2CYP2C9KMT2ALMNA | |
| SCHEMBL11881667 | 0.60 | MMP2 (0.41) | CYP2C9SMN1; SMN2CFTRGOPC | |
| SCHEMBL28548234 | 0.59 | HCAR2 (0.53) | SMN1; SMN2CFTRGOPC | |
| SCHEMBL3641710 | 0.58 | BACE1 (0.33) | BACE1BACE2CYP2C9KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931790-A1 | ACTINICALLY-CROSSLINKABLE AMPHIPHILIC PREPOLYMERS | Novartis AG (CH) | 2015-10-21 | — | — | EP | disclosed |
| WO-2014093756-A1 | ACTINICALLY-CROSSLINKABLE AMPHIPHILIC PREPOLYMERS | NOVARTIS AG (CH) | 2014-06-19 | — | — | WO | disclosed |
| EP-2034994-A2 | NF-KAPPA B INHIBITORS AND USES THEREOF | The Board Of Trustees Operating Michigan State University (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007133790-A2 | NF-ϰB INHIBITORS AND USES THEREOF | THE BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2007-11-22 | — | — | WO | disclosed |
| US-4009039-A | Heat developable light-sensitive oxazoline containing element | FUJI PHOTO FILM CO., LTD. (JA) | 1977-02-22 | — | — | US | disclosed |