Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293057 | 0.94 | LMNA (0.72) | LMNAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31556370 | 0.94 | LMNA (0.72) | LMNAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7044556 | 0.89 | CYP3A4 (0.55) | LMNAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11351362 | 0.89 | ALDH1A1 (0.55) | LMNAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9911067 | 0.89 | GAA (0.72) | LMNAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23523217 | 0.88 | ALDH1A1 (0.53) | LMNAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2909364 | 0.88 | HSD17B10 (0.59) | LMNAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9812945 | 0.88 | KMT2A (0.56) | LMNAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1432111 | 0.88 | KMT2A (0.58) | LMNAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL217079 | 0.88 | CYP3A4 (0.56) | LMNAALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |
| EP-0492999-B1 | Copolyester and hollow container and oriented film comprising the copolyester | MITSUBISHI CHEM CORP (JP) | 2002-05-22 | — | — | EP | disclosed |
| US-6254950-B1 | BLEND WITH POLYETHYLENE TEREPHTHALATE AND NAPHTHALATE, POLYBUTYLENE AND POLYTRIMETHYLENE TEREPHTHALATE, AND/OR POLYBUTYLENE NAPHTHALATE; PACKAGING | EASTMAN CHEMICAL COMPANY | 2001-07-03 | — | — | US | disclosed |
| US-5239045-A | Containing terephthalic acid, phenylenedioxy/diacetic acid, diol; packaging | MITSUBISHI KASEI CORPORATION (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0492999-A2 | Copolyester and hollow container and oriented film comprising the copolyester | Mitsubishi Chemical Corporation (JP) | 1992-07-01 | — | — | EP | disclosed |