Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076916 | 0.88 | LMNA (0.62) | KMT2AALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14548592 | 0.84 | MTNR1A (0.46) | KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL1438962 | 0.84 | PPARA (0.59) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7293057 | 0.83 | LMNA (0.72) | KMT2AALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31556370 | 0.83 | LMNA (0.72) | KMT2AALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14501385 | 0.83 | PSEN1 (0.45) | KMT2AALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL874138 | 0.82 | KMT2A (0.62) | KMT2AALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14407408 | 0.82 | PPARG (0.44) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL7396086 | 0.82 | KMT2A (0.61) | KMT2AALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2832791 | 0.82 | SMN1; SMN2 (0.59) | KMT2AALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2574605-B1 | Processes for preparing cyclopentenones and cyclopentenones for the synthesis of benzindene prostaglandins | CHIROGATE INT INC (TW) | 2017-09-27 | — | — | EP | disclosed |
| EP-2574605-A1 | Processes for preparing cyclopentenones and cyclopentenones for the synthesis of benzindene prostaglandins | Chirogate International Inc. (TW) | 2013-04-03 | — | — | EP | disclosed |
| US-8350090-B1 | Processes for preparing cyclopentenones and cyclopentenones for the synthesis of benzindene prostaglandins | CHIROGATE INTERNATIONAL INC. (TW) | 2013-01-08 | — | — | US | disclosed |
| US-7220773-B2 | Heterocylic amines used as antidiabetic or hyperglycemic agents | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7220773-B2 | Heterocylic amines used as antidiabetic or hyperglycemic agents | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| EP-0223593-B1 | PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 1991-08-07 | — | — | EP | disclosed |
| EP-0223593-A2 | Phenoxyalkylcarboxylic acids and esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1987-05-27 | — | — | EP | disclosed |