⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554595 | 0.80 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL6049694 | 0.76 | GABRA1 (0.43) | — | |
| SCHEMBL2051992 | 0.68 | GABRA1 (0.39) | — | |
| SCHEMBL28576004 | 0.64 | GABRA1 (0.43) | — | |
| SCHEMBL9271255 | 0.64 | GABRA1 (0.52) | — | |
| SCHEMBL893214 | 0.63 | GABRA1 (0.44) | — | |
| SCHEMBL22356520 | 0.63 | FABP3 (0.38) | — | |
| SCHEMBL20543189 | 0.63 | TRPA1 (0.50) | — | |
| SCHEMBL18780053 | 0.62 | LTA4H (0.44) | — | |
| SCHEMBL9363718 | 0.62 | HSP90AB1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058320-B1 | Process for preparing water-soluble phosphonooxymethyl derivatives of alcohol and phenol | GUILFORD PHARM INC (US) | 2012-11-21 | — | — | EP | disclosed |
| US-7534776-B2 | Process for preparing water-soluble phosphonooxymethyl derivatives of alcohol and phenol | EISAI CORPORATION OF NORTH AMERICA (US) | 2009-05-19 | — | — | US | disclosed |
| EP-2058320-A1 | Process for preparing water-soluble phosphonooxymethyl derivatives of alcohol and phenol | GUILFORD PHARMACEUTICALS INC. (US) | 2009-05-13 | — | — | EP | disclosed |
| EP-1471920-B1 | PROCESS FOR PREPARING WATER-SOLUBLE PHOSPHONOOXYMETHYL DERIVATIVES OF ALCOHOL AND PHENOL | GUILFORD PHARM INC (US) | 2009-02-25 | — | — | EP | disclosed |
| US-7229978-B2 | Process for preparing water soluble phosphonooxymethyl derivatives of alcohol and phenol | MGI GP, INC. (US) | 2007-06-12 | — | — | US | disclosed |
| US-20070043206-A1 | Process for preparing water-soluble phosphonooxymethyl derivatives of alcohol and phenol | MGI GP, INC. (US) | 2007-02-22 | — | — | US | disclosed |
| EP-1471920-A4 | PROCESS FOR PREPARING WATER-SOLUBLE PHOSPHONOOXYMETHYL DERIVATIVES OF ALCOHOL AND PHENOL | GUILFORD PHARM INC (US) | 2006-02-15 | — | — | EP | disclosed |
| US-20050124787-A1 | Process for preparing water soluble phosphonooxymethyl derivatives of alcohol and phenol | EISAI INC. | 2005-06-09 | — | — | US | disclosed |
| EP-1471920-A2 | PROCESS FOR PREPARING WATER-SOLUBLE PHOSPHONOOXYMETHYL DERIVATIVES OF ALCOHOL AND PHENOL | GUILFORD PHARMACEUTICALS INC. (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003059255-A2 | PROCESS FOR PREPARING WATER-SOLUBLE PHOSPHONOOXYMETHYL DERIVATIVES OF ALCOHOL AND PHENOL | GUILFORD PHARMACEUTICALS, INC. (US) | 2003-07-24 | — | — | WO | disclosed |