SCHEMBL4077495

SCHEMBL4077495

CC(C)O[Si](CCl)(OC(C)C)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.34
TSHR P16473 2/20 0.32
TRPA1 O75762 1/20 0.32
ALDH1A1 P00352 3/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TP53 P04637 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703426 0.83 TSHR (0.33) LMNATSHRALDH1A1L3MBTL1
SCHEMBL704437 0.83 TSHR (0.33) LMNATSHRALDH1A1L3MBTL1
SCHEMBL706392 0.82 TSHR (0.32) LMNATSHRALDH1A1HTTL3MBTL1
SCHEMBL703879 0.80 TSHR (0.32) LMNATSHRALDH1A1L3MBTL1
SCHEMBL4087294 0.80 TSHR (0.32) LMNATSHRALDH1A1L3MBTL1TP53
SCHEMBL707187 0.80 TSHR (0.32) LMNATSHRALDH1A1L3MBTL1
SCHEMBL27618717 0.80 TAAR1 (0.38) TSHRALDH1A1L3MBTL1
SCHEMBL4078011 0.80 TSHR (0.32) LMNATSHRALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL27730630 0.80 TSHR (0.35) LMNATSHRTRPA1ALDH1A1HPGD
SCHEMBL4082976 0.80 TSHR (0.32) LMNATSHRTRPA1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-0068813-B1 FUNGICIDAL 1,2,4-TRIAZOLE AND IMIDAZOLE DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-09-25 EP disclosed
US-4510136-A A 1-SILYLMETHYL DERIVATIVE; AGRICULTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-09 US disclosed
US-4496551-A Fungicidal imidazole derivatives E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-01-29 US disclosed
EP-0068813-A2 Fungicidal 1,2,4-triazole and imidazole derivatives E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-05 EP disclosed