Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | GLI1 | P08151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073276 | 0.81 | L3MBTL1 (0.33) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL4152747 | 0.72 | — | — | |
| SCHEMBL3830497 | 0.72 | — | — | |
| SCHEMBL31436261 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL5709800 | 0.71 | FDPS (0.42) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL24531742 | 0.67 | FDPS (0.50) | MAPTKMT2ACYP2D6 | |
| SCHEMBL19820361 | 0.67 | FDPS (0.50) | MAPTKMT2ACYP2D6 | |
| SCHEMBL3086112 | 0.67 | FDPS (0.50) | MAPTKMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL29642935 | 0.66 | FDPS (0.49) | MAPTKMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL5709804 | 0.66 | FDPS (0.49) | MAPTKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |