SCHEMBL3086112

SCHEMBL3086112

NC(=O)CC1CCCCN1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.50
KMT2A Q03164 3/20 0.46
CYP2D6 P10635 2/20 0.46
MEN1 O00255 2/20 0.46
LMNA P02545 2/20 0.46
TP53 P04637 2/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP1A2 P05177 1/20 0.46
TSHR P16473 1/20 0.46
MLNR O43193 1/20 0.46
ABCB11 O95342 1/20 0.46
EGFR P00533 1/20 0.46
FYN P06241 1/20 0.46
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
HTR1A P08908 1/20 0.46
CHRM5 P08912 1/20 0.46
ADRA2A P08913 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CHRM1 P11229 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24531742 1.00 FDPS (0.50) FDPSKMT2ACYP2D6MEN1LMNA
SCHEMBL19820361 1.00 FDPS (0.50) FDPSKMT2ACYP2D6MEN1LMNA
Hydrochloric Acid SCHEMBL5709804 0.98 FDPS (0.49) FDPSKMT2ACYP2D6MEN1LMNA
Hydrochloric Acid SCHEMBL31436221 0.98 FDPS (0.49) FDPSKMT2ACYP2D6MEN1LMNA
Hydrochloric Acid SCHEMBL29642935 0.98 FDPS (0.49) FDPSKMT2ACYP2D6MEN1LMNA
SCHEMBL31436261 0.94
SCHEMBL3830497 0.94
SCHEMBL4152747 0.94
Hydrochloric Acid SCHEMBL5709800 0.92 FDPS (0.42) FDPSKMT2ACYP2D6MEN1LMNA
SCHEMBL11666395 0.83 FDPS (0.53) FDPSKMT2ACYP2D6MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497364-B2 Compound for the determination of the protein FKBP12 and a sensor unit comprising it UNIVERSITA DEGLI STUDI DI FIRENZE (IT) 2025-12-16 US claimed
WO-2017024010-A1 3-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF SAMUMED, LLC. (US) 2017-02-09 WO claimed
EP-1606283-B1 P38 INHIBITORS AND METHODS OF USE THEREOF ARRAY BIOPHARMA INC (US) 2008-10-08 EP claimed
EP-1901747-A2 PYRIMIDINE-BASED CDK INHIBITORS FOR TREATING PAIN Ingenium Pharmaceuticals AG (DE) 2008-03-26 EP claimed
WO-2006125616-A2 PYRIMIDINE-BASED CDK INHIBITORS FOR TREATING PAIN INGENIUM PHARMACEUTICALS AG (DE) 2006-11-30 WO claimed
US-7135575-B2 P38 inhibitors and methods of use thereof ARRAY BIOPHARMA, INC. (US) 2006-11-14 US claimed
EP-1606244-A2 CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT Abbott Laboratories (US) 2005-12-21 EP claimed
US-20040209858-A1 Cycloalkylamides and their therapeutic applications ABBOTT LABORATORIES 2004-10-21 US claimed
WO-2004037769-A2 CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT ABBOTT LABORATORIES (US) 2004-05-06 WO claimed
US-20040077618-A1 Cycloalkylamides and their therapeutic applications ABBOTT LABORATORIES 2004-04-22 US claimed
CN-1100777-C N-heterocyclic derivatives as NOS inhibitor BERLEX LAB (US) 2003-02-05 CN claimed
CN-1252799-A N-heterocyclic derivatives as NOS inhibitor BERLEX LAB (US) 2000-05-10 CN claimed
US-4791199-A Process for antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones G. D. SEARLE & CO. (US) 1988-12-13 US claimed
EP-0234331-A1 Octahydropyrido[1,2-c]-pyrimidinones G.D. Searle & Co. (US) 1987-09-02 EP claimed
EP-0215477-A1 Process and intermediates for antiarrhytmic 1,3-diazabicyclo/4.4.0/dec-2-en-4-ones G.D. Searle & Co. (US) 1987-03-25 EP claimed
WO-2025125302-A1 NOVEL COMPOUNDS GENOME THERAPEUTICS LTD (GB) 2025-06-19 WO disclosed
US-11773078-B2 Furin inhibitors GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2023-10-03 US disclosed
EP-0823254-A1 NOVEL USE OF PYRAZOLOPYRIDINE COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-02-11 EP disclosed
EP-0234331-A1 Octahydropyrido[1,2-c]-pyrimidinones G.D. Searle & Co. (US) 1987-09-02 EP disclosed
US-4680295-A ANTIARRHYTHMIA AGENTS G. D. SEARLE & CO. (US) 1987-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040209858-A1 Cycloalkylamides and their therapeutic applications GAP43, SCN1B, GRIN2B FDPS 1236/4885KMT2A 3330/4885CYP2D6 788/4885
US-12497364-B2 Compound for the determination of the protein FKBP12 and a sensor unit comprising it FKBP14, FKBP5, FKBP1A FDPS 407/4885KMT2A 4654/4885CYP2D6 2705/4885
US-20040077618-A1 Cycloalkylamides and their therapeutic applications GAP43, SCN1B, GRIN2B FDPS 1236/4885KMT2A 3330/4885CYP2D6 788/4885
US-11773078-B2 Furin inhibitors FURIN, TGFB1, PCSK7 FDPS 427/4885KMT2A 4129/4885CYP2D6 2965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.