Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962881 | 0.88 | MAPT (0.39) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL3961456 | 0.81 | MMP2 (0.46) | — | |
| SCHEMBL1464501 | 0.80 | MAPT (0.56) | MAPTALDH1A1HTTLMNAGAA | |
| SCHEMBL1463571 | 0.78 | MAPT (0.52) | MAPTALDH1A1HTTLMNAGAA | |
| SCHEMBL3969923 | 0.78 | ALDH1A1 (0.40) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL351726 | 0.76 | EEF2K (0.58) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL3962907 | 0.76 | MAPT (0.37) | MAPTALDH1A1LMNAGAAMEN1 | |
| SCHEMBL3963914 | 0.75 | CNR2 (0.47) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL3963604 | 0.75 | MAPT (0.43) | MAPTALDH1A1HTTLMNAATM | |
| SCHEMBL1463591 | 0.73 | EEF2K (0.55) | MAPTALDH1A1HTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |