Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 8/20 | 0.36 |
| ▸ | MMP13 | P45452 | 8/20 | 0.36 |
| ▸ | MMP9 | P14780 | 7/20 | 0.36 |
| ▸ | MMP3 | P08254 | 6/20 | 0.36 |
| ▸ | MMP8 | P22894 | 6/20 | 0.36 |
| ▸ | MMP14 | P50281 | 6/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961452 | 0.94 | MMP2 (0.45) | MMP2MMP13MMP9MMP3MMP8 | |
| SCHEMBL3962881 | 0.88 | MAPT (0.39) | MAPTALDH1A1GAALMNAMEN1 | |
| SCHEMBL3961456 | 0.82 | MMP2 (0.46) | MMP2MMP13MMP9MMP3MMP8 | |
| SCHEMBL1463767 | 0.79 | MAPT (0.45) | MAPTMMP2MMP13MMP9MMP3 | |
| SCHEMBL3962985 | 0.78 | MLYCD (0.40) | MAPTMMP2MMP13MMP9MMP3 | |
| SCHEMBL3967700 | 0.77 | MMP2 (0.47) | MAPTMMP2MMP13MMP9MMP3 | |
| SCHEMBL1464281 | 0.77 | MMP2 (0.51) | MAPTMMP2MMP13MMP9MMP3 | |
| SCHEMBL4078069 | 0.76 | MAPT (0.41) | MAPTALDH1A1GAALMNAMEN1 | |
| SCHEMBL1463749 | 0.75 | MMP2 (0.42) | MAPTMMP2MMP13MMP9MMP3 | |
| SCHEMBL3959480 | 0.74 | P2RX7 (0.43) | MAPTMMP2MMP13MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |