SCHEMBL407819

SCHEMBL407819

CN(NC(=O)C(=O)O)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM5B Q9UGL1 1/20 0.35
MME P08473 1/20 0.31
ACE P12821 1/20 0.31
GPR35 Q9HC97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1644186 0.79 ALDH1A1 (0.32)
SCHEMBL21585749 0.70 EGLN1 (0.44) MMEACEGPR35
SCHEMBL18488505 0.62
SCHEMBL407504 0.62 KDM4E (0.44) KDM5BMMEACE
Oxalic Acid SCHEMBL10733846 0.61 ALDH1A1 (0.35)
Oxalic Acid SCHEMBL10733835 0.61 ALDH1A1 (0.35)
SCHEMBL669001 0.61 KDM5B (0.42) KDM5B
SCHEMBL408136 0.60 TSHR (0.33)
SCHEMBL29420093 0.58 KDM4C (0.45) KDM5B
Bicarbonate SCHEMBL10734019 0.58 ALDH1A1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2394986-B1 3-AMINOXALYLAMINOBENZAMIDE DERIVATIVES, AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT AGRO KANESHO CO LTD (JP) 2013-12-04 EP disclosed
US-8541473-B2 3-aminoxalyl-aminobenzamide derivatives and insecticidal and miticidal agents containing same as active ingredient AGRO-KANESHO CO., LTD. (JP) 2013-09-24 US disclosed
US-20120022263-A1 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT AGRO-KANESHO CO., LTD. (JP) 2012-01-26 US disclosed
EP-2394986-A1 3-AMINOXALYLAMINOBENZAMIDE DERIVATIVES, AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT Agro-Kanesho Co., Ltd. (JP) 2011-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022263-A1 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT HDHD5, CBR3, BAK1 KDM5B 640/4885MME 381/4885ACE 719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.