Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407819 | 0.79 | KDM5B (0.35) | — | |
| SCHEMBL7718758 | 0.70 | POLB (0.38) | POLB | |
| SCHEMBL21585749 | 0.69 | EGLN1 (0.44) | ALDH1A1 | |
| SCHEMBL1526296 | 0.69 | — | — | |
| Formic Acid SCHEMBL4660060 | 0.67 | — | — | |
| SCHEMBL18488505 | 0.65 | — | — | |
| SCHEMBL9740779 | 0.65 | — | — | |
| Dimethylamine SCHEMBL15271682 | 0.65 | KDM7A (0.44) | KDM7APHF8KDM2A | |
| SCHEMBL25352936 | 0.62 | SLC6A5 (0.37) | — | |
| Bicarbonate SCHEMBL10734019 | 0.61 | ALDH1A1 (0.37) | ALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267303-A1 | Compounds and Methods for Treating or Preventing Bacterial Infections | BAYLOR COLLEGE OF MEDICINE | 2022-08-25 | — | — | US | disclosed |
| US-8633323-B2 | Process for preparing bis(thiohydrazide amides) | SYNTA PHARMACEUTICALS CORP. (US) | 2014-01-21 | — | — | US | disclosed |
| US-20110098476-A1 | PROCESS FOR PREPARING BIS(THIOHYDRAZIDE AMIDES) | SYNTA PHARMACEUTICALS CORP. | 2011-04-28 | — | — | US | disclosed |
| WO-2009123704-A2 | PROCESS FOR PREPARING BIS(THIOHYDRAZIDE AMIDES) | SYNTA PHARMACEUTICALS CORP. (US) | 2009-10-08 | — | — | WO | disclosed |
| EP-1737851-A1 | TETRAHYDROBENZAZEPINE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS (ANTIPSYCHOTIC AGENTS) | GLAXO GROUP LIMITED (GB) | 2007-01-03 | — | — | EP | disclosed |
| EP-1124827-B1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2005-11-30 | — | — | EP | disclosed |
| WO-2005087764-A1 | TETRAHYDROBENZAZEPINE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS (ANTIPSYCHOTIC AGENTS) | GLAXO GROUP LIMITED (GB) | 2005-09-22 | — | — | WO | disclosed |
| US-6413997-B1 | INSECTICIDES, MITICIDES | DOW AGROSCIENCES LLC | 2002-07-02 | — | — | US | disclosed |
| EP-0922043-B1 | PESTICIDAL 3-(SUBSTITUTED PHENYL)-5-(THIENYL OR FURYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-6262305-B1 | Process and intermediates for preparing 3-(substituted phenyl)-5-(thienyl or furyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2001-07-17 | — | — | US | disclosed |
| EP-1113004-A2 | Intermediates for producing 3-(substituted phenyl)-5-(thienyl or furyl)-1,2,4-triazole compounds | Dow Agrosciences LLC (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6015826-A | INSECTICIDES, APHIDICIDES, AND MITICIDES | DOW AGROSCIENCES LLC | 2000-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267303-A1 | Compounds and Methods for Treating or Preventing Bacterial Infections | OXA1L, MMP8, OGG1 | ALDH1A1 349/4885TSHR 4547/4885POLB 206/4885 |
| US-20110098476-A1 | PROCESS FOR PREPARING BIS(THIOHYDRAZIDE AMIDES) | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-3, CYB5R3 | ALDH1A1 1070/4885TSHR 7/4885POLB 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.