Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137047 | 0.85 | CYP19A1 (0.52) | KMT2ANPC1RAB9ATDP1ATM | |
| SCHEMBL11467265 | 0.83 | CYP19A1 (0.50) | KMT2ANPC1RAB9ATDP1ATM | |
| SCHEMBL4095285 | 0.82 | KMT2A (0.52) | KMT2ARAB9AGAASMN1; SMN2MEN1 | |
| SCHEMBL10499600 | 0.81 | RNF4 (0.57) | NPC1RAB9AFFAR1SMN1; SMN2CYP19A1 | |
| SCHEMBL17951284 | 0.79 | KMT2A (0.78) | KMT2ANPC1RAB9AFFAR1FFAR4 | |
| SCHEMBL18566942 | 0.78 | CYP19A1 (0.55) | KMT2APPARGPPARASMN1; SMN2TDP1 | |
| SCHEMBL10390223 | 0.78 | RAB9A (0.50) | KMT2ANPC1RAB9APPARGPPARA | |
| SCHEMBL717987 | 0.78 | NPC1 (0.65) | KMT2ATAAR1NPC1RAB9AGAA | |
| SCHEMBL11839597 | 0.78 | ALDH1A1 (0.62) | KMT2ASMN1; SMN2MEN1CYP19A1 | |
| SCHEMBL3154002 | 0.77 | CYP19A1 (0.58) | KMT2ASMN1; SMN2TDP1ATMCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845970-A4 | TUMOR NECROSIS FACTOR INHIBITORS | CEPTION THERAPEUTICS INC (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1845970-A2 | TUMOR NECROSIS FACTOR INHIBITORS | Ception Therapeutics, Inc. (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006083970-A2 | TUMOR NECROSIS FACTOR INHIBITORS | CEPTION THERAPEUTICS, INC. (US) | 2006-08-10 | — | — | WO | disclosed |