Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.55 |
| ▸ | IKBKB | O14920 | 3/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29712321 | 1.00 | BCAT2 (0.55) | BCAT2IKBKBKEAP1NFE2L2PARP1 | |
| SCHEMBL29437046 | 0.92 | IKBKB (0.47) | BCAT2IKBKBKEAP1NFE2L2PARP1 | |
| SCHEMBL29771871 | 0.89 | IKBKB (0.49) | BCAT2IKBKBKEAP1NFE2L2PARP1 | |
| SCHEMBL27214460 | 0.88 | BCAT2 (0.63) | BCAT2IKBKBKEAP1NFE2L2PARP1 | |
| SCHEMBL3787229 | 0.87 | PARP1 (0.48) | BCAT2IKBKBKEAP1NFE2L2PARP1 | |
| SCHEMBL6748515 | 0.86 | MAPT (0.52) | BCAT2IKBKBMAPTGAAMMP2 | |
| SCHEMBL4077919 | 0.86 | MMP2 (0.57) | MAPTGAAMMP2KDM4EALDH1A1 | |
| SCHEMBL28027873 | 0.86 | BCAT2 (0.62) | BCAT2IKBKBKEAP1NFE2L2PARP1 | |
| SCHEMBL27704997 | 0.84 | BCAT2 (0.59) | BCAT2IKBKBKEAP1NFE2L2PARP1 | |
| SCHEMBL7143112 | 0.84 | PLK4 (0.49) | IKBKBKEAP1NFE2L2PARP1MAP2K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101215259-A | Pyridines derivatives, pharmacological receivable salt thereof, composition containing the said substances and use thereof | HANGZHOU NEW RAYJAY BIOMED COR (CN) | 2008-07-09 | — | — | CN | claimed |
| CN-109790143-A | Amine-linked C for target protein degradation3-glutarimide solution stator body | C4医药公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109641874-A | C for target protein degradation3The glutarimide degron body of carbon connection | C4医药公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109562113-A | Spirocyclo-rongeur for target protein degradation | C4医药公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109562107-A | Heterocyclic degrading ligand for target protein degradation | C4医药公司 | 2019-04-02 | — | — | CN | disclosed |
| US-9884806-B2 | Cyclic vinylogous amides as bromodomain inhibitors | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2018-02-06 | — | — | US | disclosed |
| EP-2367822-B1 | TRICYCLIC AZAINDOLES | MERCK PATENT GMBH (DE) | 2016-10-05 | — | — | EP | disclosed |
| US-20160200666-A1 | CYCLIC VINYLOGOUS AMIDES AS BROMODOMAIN INHIBITORS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2016-07-14 | — | — | US | disclosed |
| US-8853391-B2 | Tricyclic azaindoles | MERCK PATENT GMBH (DE) | 2014-10-07 | — | — | US | disclosed |
| CN-101535412-B | New ds DNA binding fluorescent dyes | HOFFMANN LA ROCHE | 2014-05-07 | — | — | CN | disclosed |
| CN-101367748-A | Amide derivatives, process for production of the same, and method for application thereof as insecticide | MITSUI CHEMICALS INC (JP) | 2009-02-18 | — | — | CN | disclosed |
| CN-101215259-A | Pyridines derivatives, pharmacological receivable salt thereof, composition containing the said substances and use thereof | HANGZHOU NEW RAYJAY BIOMED COR (CN) | 2008-07-09 | — | — | CN | disclosed |
| CN-101208009-A | Composition for preventing and removing pest | MITSUI CHEMICALS INC (JP) | 2008-06-25 | — | — | CN | disclosed |
| CN-101203132-A | Insecticidal and bactericidal composition | MITSUI CHEMICALS INC (JP) | 2008-06-18 | — | — | CN | disclosed |
| CN-101203485-A | Amide derivative, pesticide containing such compound and use thereof | MITSUI CHEMICALS INC (JP) | 2008-06-18 | — | — | CN | disclosed |
| CN-101203484-A | Amide derivative and pesticide containing such compound | MITSUI CHEMICALS INC (JP) | 2008-06-18 | — | — | CN | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| CN-1926094-A | Amide derivatives, process for their preparation and their use as pesticides | MITSUI CHEMICALS INC (JP) | 2007-03-07 | — | — | CN | disclosed |
| CN-1871209-A | Agricultural and horticultural insecticide and method of use thereof | MITSUI CHEMICALS INC (JP) | 2006-11-29 | — | — | CN | disclosed |
| CN-1863769-A | Process for preparing aminopyrrolidine derivatives and intermediate compounds | TEIJIN PHARMA LTD (JP) | 2006-11-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200666-A1 | CYCLIC VINYLOGOUS AMIDES AS BROMODOMAIN INHIBITORS | BRD1, BRD4, BRDT | BCAT2 146/4885IKBKB 2077/4885KEAP1 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.