SCHEMBL4077919

SCHEMBL4077919

Nc1cccc(C(=O)O)c1-c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.57
HNF4A P41235 1/20 0.53
ALDH1A1 P00352 4/20 0.50
FABP4 P15090 3/20 0.50
ALOX15 P16050 1/20 0.50
GAA P10253 2/20 0.49
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
HPGD P15428 1/20 0.49
MAPT P10636 4/20 0.47
KDM4E B2RXH2 3/20 0.47
CDC25B P30305 2/20 0.47
GFER P55789 2/20 0.47
PIM1 P11309 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MYC P01106 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
LMNA P02545 1/20 0.47
G6PD P11413 1/20 0.47
CASP7 P55210 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17744792 0.94 MMP2 (0.59) MMP2HNF4AALDH1A1FABP4ALOX15
SCHEMBL29568880 0.94 MMP2 (0.59) MMP2HNF4AALDH1A1FABP4ALOX15
SCHEMBL17744870 0.90 MMP2 (0.55) MMP2HNF4AALDH1A1FABP4ALOX15
SCHEMBL30086172 0.90 MMP2 (0.55) MMP2HNF4AALDH1A1FABP4ALOX15
SCHEMBL707849 0.89 MMP2 (0.53) MMP2HNF4AALDH1A1FABP4ALOX15
SCHEMBL6748515 0.88 MAPT (0.52) MMP2HNF4AALDH1A1FABP4GAA
SCHEMBL407835 0.86 BCAT2 (0.55) MMP2HNF4AALDH1A1GAAHPGD
SCHEMBL29712321 0.86 BCAT2 (0.55) MMP2HNF4AALDH1A1GAAHPGD
SCHEMBL9188681 0.85 MCL1 (0.57) MMP2HNF4AALDH1A1ALOX15GAA
SCHEMBL70098 0.85 HNF4A (0.63) HNF4AALDH1A1FABP4ALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116406253-A Powder-containing composition 株式会社资生堂 2023-07-07 CN disclosed
CN-109790405-A Form the composition of dielectric film 富士胶片电子材料美国有限公司 2019-05-21 CN disclosed
CN-105392838-B Composition epoxy resin, prepreg and carbon fibre reinforced composite 东丽株式会社 2018-12-14 CN disclosed
US-20160206581-A1 TREATMENT AND PREVENTION OF AUTISM AND AUTISM SPECTRUM DISORDERS WITTKOWSKI, Knut M. (US) 2016-07-21 US disclosed
CN-105392838-A Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES 2016-03-09 CN disclosed
CN-102348709-B Material for organic electroluminescent device MERCK PATENT GMBH 2014-11-19 CN disclosed
CN-102348709-A Material for organic electroluminescent device MERCK PATENT GMBH 2012-02-08 CN disclosed
CN-101495918-A Photosensitive surface printing plate material KONICA MINOLTA MED & GRAPHIC (JP) 2009-07-29 CN disclosed
EP-2074120-A1 TROPANE COMPOUNDS Exelixis, Inc. (US) 2009-07-01 EP disclosed
WO-2009055077-A1 TROPANE COMPOUNDS EXELIXIS, INC. (US) 2009-04-30 WO disclosed
CN-1365277-A Methods of treating chronic pain using MEK inhibitors VARNER LAMBERT CO (US) 2002-08-21 CN disclosed