SCHEMBL4078522

SCHEMBL4078522

Nc1ccn([C@H]2C[C@H](OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)C[C@@H]3O)[C@@H](COP(=O)(O)O)O2)c(=O)n1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 4/20 0.62
▸ P2RY4 P51582 4/20 0.62
▸ P2RY6 Q15077 3/20 0.62
▸ POLB P06746 2/20 0.62
▸ FUT5 Q11128 1/20 0.53
▸ F2 P00734 2/20 0.52
▸ TGM2 P21980 1/20 0.47
▸ TERT O14746 1/20 0.47
▸ NT5E P21589 2/20 0.47
▸ P2RY1 P47900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29702417 1.00 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL29424735 1.00 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL29365434 1.00 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL29371610 1.00 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL29551697 0.96 P2RY2 (0.61) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL29365163 0.96 P2RY2 (0.61) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL8613676 0.95 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL8614074 0.95 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL15698310 0.95 P2RY2 (0.56) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL30839331 0.95 P2RY2 (0.57) P2RY2P2RY4P2RY6POLBFUT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240173390-A1 PEPTIDE VACCINE FORMULATIONS AND USE THEREOF FOR INDUCING AN IMMUNE RESPONSE THE U.S.A, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-05-30 — — US disclosed
US-11938177-B2 Peptide vaccine formulations and use thereof for inducing an immune response THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-03-26 — — US disclosed
US-20230026627-A1 Compositions and Methods of Manufacturing Star Polymers for Ligand Display and/or Drug Delivery VACCITECH NORTH AMERICA, INC. (US) 2023-01-26 — — US disclosed
US-20220152170-A1 PEPTIDE VACCINE FORMULATIONS AND USE THEREOF FOR INDUCING AN IMMUNE RESPONSE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2022-05-19 — — US disclosed
EP-3955964-A1 COMPOSITIONS AND METHODS OF MANUFACTURING STAR POLYMERS FOR LIGAND DISPLAY AND/OR DRUG DELIVERY Avidea Technologies, Inc. (US) 2022-02-23 — — EP disclosed
US-11191821-B2 Peptide vaccine formulations and use thereof for inducing an immune response THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2021-12-07 — — US disclosed
US-20210353740-A1 HIV-1 ENV FUSION PEPTIDE NANOPARTICLE CARRIER CONJUGATES AND THEIR USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2021-11-18 — — US disclosed
US-20210128727-A1 A pharmaceutical combination for use in the treatment of cancer UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZ (DE) 2021-05-06 — — US disclosed
EP-3790582-A1 A PHARMACEUTICAL COMBINATION FOR USE IN THE TREATMENT OF CANCER Universitätsmedizin der Johannes Gutenberg-Universität Mainz (DE) 2021-03-17 — — EP disclosed
US-20210023208-A1 EXPRESSION VECTOR DELIVERY SYSTEM AND USE THEREOF FOR INDUCING AN IMMUNE RESPONSE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2021-01-28 — — US disclosed
EP-1567863-A4 METHODS OF THERAPY AND DIAGNOSIS NUVELO INC (US) 2007-10-03 — — EP disclosed
EP-1483407-A4 METHODS OF THERAPY AND DIAGNOSIS NUVELO INC (US) 2006-11-15 — — EP disclosed
US-20050281813-A1 Methods of therapy and diagnosis using targeting of cells that express toll-like receptor proteins NUVELO, INC. (US) 2005-12-22 — — US disclosed
EP-1567863-A2 METHODS OF THERAPY AND DIAGNOSIS Nuvelo, Inc. (US) 2005-08-31 — — EP disclosed
WO-2005052126-A2 BIOLOGICALLY ACTIVE ANTIBODIES RECOGNIZING A CELL SURFACE MOLECULE SELECTIVELY EXPRESSED ON LIVING MOUSE NATURAL TYPE ONE (I) INTERFERON PRODUCING CELLS WASHINGTON UNIVERSITY IN ST. LOUIS (US) 2005-06-09 — — WO disclosed
EP-1483407-A2 METHODS OF THERAPY AND DIAGNOSIS Nuvelo, Inc. (US) 2004-12-08 — — EP disclosed
WO-2004047612-A2 METHODS OF THERAPY AND DIAGNOSIS NUVELO, INC. (US) 2004-06-10 — — WO disclosed
US-20040023870-A1 Methods of therapy and diagnosis using targeting of cells that express toll-like receptor proteins NUVELO, A CORP. OF NEVADA 2004-02-05 — — US disclosed
US-20040022786-A1 Methods of therapy and diagnosis using targeting of cells that express toll-like receptor proteins DEDEA DOUGLAS (US) 2004-02-05 — — US disclosed
WO-2003068935-A2 METHODS OF THERAPY AND DIAGNOSIS NUVELO, INC. (US) 2003-08-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240173390-A1 PEPTIDE VACCINE FORMULATIONS AND USE THEREOF FOR INDUCING AN IMMUNE RESPONSE NGLY1, MYD88, SPPL2B P2RY2 4631/4885P2RY4 4468/4885P2RY6 4268/4885
US-11938177-B2 Peptide vaccine formulations and use thereof for inducing an immune response NGLY1, MYD88, SPPL2B P2RY2 4631/4885P2RY4 4468/4885P2RY6 4268/4885
US-11191821-B2 Peptide vaccine formulations and use thereof for inducing an immune response NGLY1, MYD88, SPPL2B P2RY2 4631/4885P2RY4 4468/4885P2RY6 4268/4885
US-20230026627-A1 Compositions and Methods of Manufacturing Star Polymers for Ligand Display and/or Drug Delivery TNFSF10, SELPLG, FCGRT P2RY2 219/4885P2RY4 141/4885P2RY6 174/4885
US-20220152170-A1 PEPTIDE VACCINE FORMULATIONS AND USE THEREOF FOR INDUCING AN IMMUNE RESPONSE NGLY1, MYD88, SPPL2B P2RY2 4631/4885P2RY4 4468/4885P2RY6 4268/4885
US-20210023208-A1 EXPRESSION VECTOR DELIVERY SYSTEM AND USE THEREOF FOR INDUCING AN IMMUNE RESPONSE CD69, CD14, CD4 P2RY2 3411/4885P2RY4 3954/4885P2RY6 2403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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