SCHEMBL29424735

SCHEMBL29424735

Nc1ccn(C2CC(O)C(COP(=O)(O)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3COP(=O)(O)O)O2)c(=O)n1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 4/20 0.62
▸ P2RY4 P51582 4/20 0.62
▸ P2RY6 Q15077 3/20 0.62
▸ POLB P06746 2/20 0.62
▸ FUT5 Q11128 1/20 0.53
▸ F2 P00734 2/20 0.52
▸ TGM2 P21980 1/20 0.47
▸ TERT O14746 1/20 0.47
▸ NT5E P21589 2/20 0.47
▸ P2RY1 P47900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29702417 1.00 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL4078522 1.00 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL29365434 1.00 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL29371610 1.00 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL29551697 0.96 P2RY2 (0.61) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL29365163 0.96 P2RY2 (0.61) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL8613676 0.95 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL8614074 0.95 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL15698310 0.95 P2RY2 (0.56) P2RY2P2RY4P2RY6POLBFUT5
SCHEMBL30839331 0.95 P2RY2 (0.57) P2RY2P2RY4P2RY6POLBFUT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12247200-B2 Compositions and methods for generating massively parallel nucleic acid sequencing libraries BIOO SCIENTIFIC CORPORATION (US) 2025-03-11 — — US claimed
EP-4323501-A1 GENETIC MODIFICATION OF HEPATOCYTES Beam Therapeutics Inc. (US) 2024-02-21 — — EP claimed
CN-116381228-A Reagent for capturing and detecting circulating exosomes and application thereof 上海大学 2023-07-04 — — CN claimed
WO-2022221699-A1 GENETIC MODIFICATION OF HEPATOCYTES BEAM THERAPEUTICS, INC. (US) 2022-10-20 — — WO claimed
CN-114667149-A Novel nucleobase editor and methods of use 比姆医疗股份有限公司 2022-06-24 — — CN claimed
EP-4728067-A2 METHODS AND COMPOSITIONS FOR TREATING ALPHA-1 ANTITRYPSIN DEFICIENCY Beam Therapeutics Inc. (US) 2026-04-22 — — EP disclosed
EP-4061961-B1 METHOD FOR DOUBLE STRAND SEQUENCING OXFORD NANOPORE TECH PLC (GB) 2026-04-08 — — EP disclosed
US-20260085315-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER APTAH BIO INC (US) 2026-03-26 — — US disclosed
EP-4696777-A1 CAS13 PROTEIN, AND CRISPR-CAS SYSTEM AND USE THEREOF Yoltech Therapeutics Co., Ltd (CN) 2026-02-18 — — EP disclosed
US-20260022377-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES APTAH BIO INC (US) 2026-01-22 — — US disclosed
EP-4652277-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES Aptah Bio, Inc. (US) 2025-11-26 — — EP disclosed
EP-4652278-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER Aptah Bio, Inc. (US) 2025-11-26 — — EP disclosed
EP-4034131-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES Brentano Biotechnology Associates (US) 2022-08-03 — — EP disclosed
US-20220235361-A1 RNAi Inhibition of Alpha-ENaC Expression ARROWHEAD PHARMACEUTICALS INC (US) 2022-07-28 — — US disclosed
EP-4028026-A1 NOVEL NUCLEOBASE EDITORS AND METHODS OF USING SAME Beam Therapeutics, Inc. (US) 2022-07-20 — — EP disclosed
EP-4022050-A2 COMPOSITIONS AND METHODS FOR EDITING A MUTATION TO PERMIT TRANSCRIPTION OR EXPRESSION Beam Therapeutics Inc. (US) 2022-07-06 — — EP disclosed
CN-114667149-A Novel nucleobase editor and methods of use 比姆医疗股份有限公司 2022-06-24 — — CN disclosed
US-20220112505-A1 RNAi Inhibition of Alpha-ENaC Expression ARROWHEAD PHARMACEUTICALS INC (US) 2022-04-14 — — US disclosed
US-20220073546-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES BRENTANO BIOTECHNOLOGY ASSOCIATES (US) 2022-03-10 — — US disclosed
US-11268082-B2 Nucleobase editors comprising nucleic acid programmable DNA binding proteins PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-03-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085315-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER RPRD2, RTCB, UPF1 P2RY2 2637/4885P2RY4 2341/4885P2RY6 2265/4885
US-20260022377-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES PRNP, UPF1, FUS P2RY2 1969/4885P2RY4 1893/4885P2RY6 2458/4885
US-11268082-B2 Nucleobase editors comprising nucleic acid programmable DNA binding proteins CNBP, DCLRE1B, APOBEC3C P2RY2 2666/4885P2RY4 3240/4885P2RY6 2892/4885
US-20220073546-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES NCL, PCNA, DNTT P2RY2 850/4885P2RY4 608/4885P2RY6 899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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