Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 8/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 8/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 8/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 8/20 | 0.45 |
| ▸ | LIPE | Q05469 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955558 | 1.00 | JAK2 (0.49) | JAK2TP53MAPTHTTKLK7 | |
| SCHEMBL29469256 | 0.84 | CETP (0.59) | MAPTHTTPDK1PDK2PDK3 | |
| SCHEMBL383919 | 0.84 | CETP (0.59) | MAPTHTTPDK1PDK2PDK3 | |
| SCHEMBL145213 | 0.80 | TP53 (0.48) | JAK2TP53MAPTHTTKLK7 | |
| SCHEMBL914296 | 0.78 | PDK1 (0.70) | JAK2TP53MAPTHTTKLK7 | |
| SCHEMBL3600530 | 0.78 | L3MBTL1 (0.59) | JAK2TP53MAPTHTTKLK7 | |
| SCHEMBL3149525 | 0.77 | RAB9A (0.45) | LIPE | |
| SCHEMBL29469169 | 0.77 | ALDH1A1 (0.59) | HTT | |
| SCHEMBL56441 | 0.77 | GAA (0.50) | MAPTLIPE | |
| SCHEMBL521100 | 0.77 | ALDH1A1 (0.59) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005087765-A1 | LIGANDS OF FOLLICLE STIMULATING HORMONE RECEPTOR AND METHODS OF USE THEREOF | ARENA PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | disclosed |