SCHEMBL4079005

SCHEMBL4079005

[C-]#[N+]c1ccc(N(c2cc(C(C)C)c3ccc4c(N(c5ccc(C#N)c6ccccc56)c5cccc6c5oc5ccccc56)cc(C(C)C)c5ccc2c3c54)c2cccc3c2oc2ccccc23)c2ccccc12

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4183679 0.92 KDM4E (0.37) KDM4EALDH1A1GAAMAPT
SCHEMBL15048019 0.91 KDM4E (0.36) KDM4EALDH1A1GAAMAPT
SCHEMBL4089204 0.86 KDM4E (0.34) KDM4EALDH1A1GAAMAPT
SCHEMBL23919538 0.83 LMNA (0.33) KDM4EALDH1A1GAAMAPT
SCHEMBL23849420 0.83 MEN1 (0.33) KDM4EALDH1A1GAAMAPT
SCHEMBL4080112 0.81 ALOX5 (0.35) KDM4EALDH1A1GAAMAPT
SCHEMBL4079155 0.79 ALOX5 (0.31)
SCHEMBL23849210 0.78 F2RL1 (0.32)
SCHEMBL4080113 0.78 TNKS (0.32)
SCHEMBL4078997 0.78 SIGMAR1 (0.34) KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9741938-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2017-08-22 US disclosed
US-20170148993-A1 INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC APPARATUS MAGNOLIA BLUE CORPORATION (JP) 2017-05-25 US disclosed
US-9650519-B2 Ink composition, organic electroluminescence element, and electronic apparatus SONY CORPORATION (JP) 2017-05-16 US disclosed
US-20170073528-A1 INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC APPARATUS MAGNOLIA BLUE CORPORATION (JP) 2017-03-16 US disclosed
US-20160380198-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-12-29 US disclosed
US-20160365516-A1 INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC APPARATUS JOLED INC. (JP) 2016-12-15 US disclosed
US-9466800-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2016-10-11 US disclosed
US-9312500-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-04-12 US disclosed
US-20160005976-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-01-07 US disclosed
US-20140061622-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
US-8431250-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2013-04-30 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AR, H1-4, AFF4 KDM4E 404/4885ALDH1A1 306/4885GAA 3887/4885
US-20160380198-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 KDM4E 586/4885ALDH1A1 470/4885GAA 4199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.