Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 3/20 | 0.51 |
| ▸ | MC5R | P33032 | 2/20 | 0.46 |
| ▸ | MC1R | Q01726 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079190 | 0.84 | CCKBR (0.48) | MGAMCCKBRMC5RMC1RBCHE | |
| SCHEMBL250139 | 0.81 | MC1R (0.60) | MC5RMC1RMEN1MAPTKMT2A | |
| SCHEMBL29874992 | 0.81 | MC1R (0.60) | MC5RMC1RMEN1MAPTKMT2A | |
| SCHEMBL10518274 | 0.75 | CCKBR (0.75) | CCKBR | |
| SCHEMBL29362407 | 0.73 | MGAM (1.00) | MGAMPDGFRBPDGFRARAB9AHSD17B10 | |
| SCHEMBL28048 | 0.73 | MGAM (1.00) | MGAMPDGFRBPDGFRARAB9AHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL27447121 | 0.71 | MGAM (0.96) | MGAMPDGFRBPDGFRARAB9AHSD17B10 | |
| Hydrochloric Acid SCHEMBL9114407 | 0.71 | MGAM (0.96) | MGAMPDGFRBPDGFRARAB9AHSD17B10 | |
| Hydrochloric Acid SCHEMBL1649216 | 0.71 | MGAM (0.96) | MGAMPDGFRBPDGFRARAB9AHSD17B10 | |
| SCHEMBL27565246 | 0.71 | MGAM (0.96) | MGAMPDGFRBPDGFRARAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017004672-A1 | PEPTIDYL TPOR ANTAGONISTS AND USES THEREOF | POLYMERS CRC LIMITED (AU) | 2017-01-12 | — | — | WO | disclosed |
| EP-2015766-A1 | CYCLISED ALPHA-CONOTOXIN PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2009-01-21 | — | — | EP | disclosed |
| EP-1578787-A4 | NOVEL CHI-CONOTOXIN PEPTIDES (-II) | XENOME LTD (AU) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007118270-A1 | CYCLISED ALPHA-CONOTOXIN PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-10-25 | — | — | WO | disclosed |
| EP-1578787-A1 | NOVEL CHI-CONOTOXIN PEPTIDES (-II) | Xenome Ltd (AU) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004099238-A1 | NOVEL mu-CONOTOXIN PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2004-11-18 | — | — | WO | disclosed |
| WO-2004050688-A1 | NOVEL χ-CONOTOXIN PEPTIDES (-II) | XENOME LTD (AU) | 2004-06-17 | — | — | WO | disclosed |