Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL18011981 | 1.00 | CA2 (0.54) | CA2TSHRCYP3A4NFKB1NPSR1 | |
| Acetic Acid SCHEMBL29494772 | 0.94 | CA2 (0.54) | CA2TSHRCYP3A4NFKB1NPSR1 | |
| SCHEMBL633800 | 0.94 | CA2 (0.58) | CA2TSHRCYP3A4NFKB1NPSR1 | |
| SCHEMBL8747771 | 0.88 | CA2 (0.58) | CA2TSHRCYP3A4NFKB1NPSR1 | |
| SCHEMBL5079455 | 0.88 | CA2 (0.58) | CA2TSHRCYP3A4NFKB1NPSR1 | |
| SCHEMBL98742 | 0.88 | CA2 (0.58) | CA2TSHRCYP3A4NFKB1NPSR1 | |
| Potassium Ion SCHEMBL267337 | 0.88 | — | — | |
| SCHEMBL3343198 | 0.88 | CA2 (0.58) | CA2TSHRCYP3A4NFKB1NPSR1 | |
| SCHEMBL10670321 | 0.88 | CA2 (0.58) | CA2TSHRCYP3A4NFKB1NPSR1 | |
| SCHEMBL1030692 | 0.88 | CA2 (0.58) | CA2TSHRCYP3A4NFKB1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11396163-B2 | Intermediate film for laminated glass, and laminated glass | SEKISUI CHEMICAL CO., LTD. (JP) | 2022-07-26 | — | — | US | disclosed |
| US-20200238666-A1 | INTERLAYER FILM FOR LAMINATED GLASS, AND LAMINATED GLASS | SEKISUI CHEMICAL CO., LTD. (JP) | 2020-07-30 | — | — | US | disclosed |
| EP-3067336-B1 | INTERLAYER FILM FOR LAMINATED GLASS, AND LAMINATED GLASS | SEKISUI CHEMICAL CO LTD (JP) | 2019-10-09 | — | — | EP | disclosed |
| US-20170217132-A1 | INTERLAYER FILM FOR LAMINATED GLASS, AND LAMINATED GLASS | SEKISUI CHEMICAL CO., LTD. (JP) | 2017-08-03 | — | — | US | disclosed |
| US-20170072665-A1 | INTERMEDIATE FILM FOR LAMINATED GLASS, AND LAMINATED GLASS | SEKISUI CHEMICAL CO., LTD. (JP) | 2017-03-16 | — | — | US | disclosed |
| EP-2574456-B1 | Termoplastic resin sheet and laminate | SEKISUI CHEMICAL CO LTD (JP) | 2016-10-05 | — | — | EP | disclosed |
| US-20160279905-A1 | INTERLAYER FILM FOR LAMINATED GLASS, AND LAMINATED GLASS | SEKISUI CHEMICAL CO., LTD. (JP) | 2016-09-29 | — | — | US | disclosed |
| EP-3067336-A1 | INTERLAYER FILM FOR LAMINATED GLASS, AND LAMINATED GLASS | Sekisui Chemical Co., Ltd. (JP) | 2016-09-14 | — | — | EP | disclosed |
| US-20160243797-A1 | INTERMEDIATE FILM FOR LAMINATED GLASS, AND LAMINATED GLASS | SEKISUI CHEMICAL CO., LTD. (JP) | 2016-08-25 | — | — | US | disclosed |
| EP-2574456-A1 | Termoplastic resin sheet and laminate | SEKISUI CHEMICAL CO., LTD. (JP) | 2013-04-03 | — | — | EP | disclosed |
| EP-1795343-B1 | THERMOPLASTIC RESIN SHEET AND LAYERED PRODUCT | SEKISUI CHEMICAL CO LTD (JP) | 2012-12-12 | — | — | EP | disclosed |
| US-7563516-B2 | Thermoplastic resin sheet and laminate | SEKISUI CHEMICAL CO., LTD. (JP) | 2009-07-21 | — | — | US | disclosed |
| EP-1795343-A1 | THERMOPLASTIC RESIN SHEET AND LAYERED PRODUCT | SEKISUI CHEMICAL CO., LTD. (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-20070014976-A1 | Thermoplastic resin sheet and laminate | SEKISUI CHEMICAL CO., LTD. (JP) | 2007-01-18 | — | — | US | disclosed |