Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14237035 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRTRIM24TRIM33 | |
| SCHEMBL1663468 | 0.74 | HTR2C (0.43) | HTR2C | |
| SCHEMBL8433245 | 0.74 | DRD2 (0.49) | HTR2C | |
| SCHEMBL27881953 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TSHRTRIM24TRIM33 | |
| SCHEMBL11150148 | 0.73 | HTR2C (0.44) | HTR2C | |
| SCHEMBL28336775 | 0.73 | HTR2C (0.44) | HTR2CTSHR | |
| SCHEMBL2716395 | 0.73 | HTR2C (0.63) | HTR2C | |
| Hydrochloric Acid SCHEMBL4518439 | 0.71 | HTR2C (0.65) | HTR2C | |
| SCHEMBL27881931 | 0.71 | CYP2C9 (0.40) | ALDH1A1TSHRTRIM24TRIM33 | |
| SCHEMBL26530980 | 0.69 | HTR2C (0.80) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |