SCHEMBL1663468

SCHEMBL1663468

O=Cc1ccccc1C1CCNC1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 4/20 0.43
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
JAK3 P52333 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7719737 0.89 HTR2C (0.55) HTR2CMEN1LMNATHRBBLM
SCHEMBL817533 0.83 HTR2C (0.43) HTR2CCHRNB4CHRNA3
SCHEMBL548147 0.79 LMNA (0.52) HTR2CMEN1LMNATHRBBLM
SCHEMBL29994354 0.78 CHRNB2 (0.45) HTR2C
SCHEMBL23702941 0.78 CHRNB2 (0.45) HTR2C
SCHEMBL28533805 0.77 HTR2C (0.57) HTR2CCHRNB4CHRNA3
SCHEMBL548161 0.77 LMNA (0.50) HTR2CMEN1LMNATHRBBLM
SCHEMBL547607 0.76 LMNA (0.48) HTR2CMEN1LMNATHRBBLM
SCHEMBL31415807 0.76 LMNA (0.48) HTR2CMEN1LMNATHRBBLM
SCHEMBL14941730 0.76 PLG (0.40) HTR2CCHRNB4CHRNA3MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN claimed
CN-1882307-A Method for dyeing fibres containing keratine HENKEL KGAA (DE) 2006-12-20 CN claimed
CN-1681470-A Agent for dyeing keratinous fibres HENKEL KGAA (DE) 2005-10-12 CN claimed
CN-115960039-B Aromatic ring substituted pyridine quaternary ammonium salt derivative and preparation method and application thereof 山东大学 2024-07-12 CN disclosed
CN-116830036-A Two-component system 西托斯股份公司 2023-09-29 CN disclosed
CN-116830040-A Photopolymerizable compositions 西托斯股份公司 2023-09-29 CN disclosed
WO-2023132681-A1 PHARMACEUTICAL COMPOSITION AND FOOD COMPOSITION COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND DERIVATIVE THEREOF FOR PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASE 덕성여자대학교 산학협력단 2023-07-13 WO disclosed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN disclosed
US-9622991-B2 Hematopoietic growth factor mimetic small molecule compounds and their uses LIGAND PHARMACEUTICALS INC. (US) 2017-04-18 US disclosed
US-9144557-B2 Hematopoietic growth factor mimetic small molecule compounds and their uses LIGAND PHARMACEUTICALS INC. (US) 2015-09-29 US disclosed
US-20150252043-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2015-09-10 US disclosed
CN-101394830-A Cosmetic agents comprising purine and/or purine derivatives I HENKEL KGAA (DE) 2009-03-25 CN disclosed
US-7202265-B2 Indolinone combinatorial libraries and related products and methods for the treatment of disease SUGEN, INC. (US) 2007-04-10 US disclosed
CN-1882307-A Method for dyeing fibres containing keratine HENKEL KGAA (DE) 2006-12-20 CN disclosed
CN-1761517-A Mixing device HENKEL KGAA (DE) 2006-04-19 CN disclosed
CN-1681470-A Agent for dyeing keratinous fibres HENKEL KGAA (DE) 2005-10-12 CN disclosed
US-20050197382-A1 Indolinone combinatorial libraries and related products and methods for the treatment of disease SUGEN, INC. 2005-09-08 US disclosed
CN-1146415-C Substituted 3, 5-diphenyl-1, 2, 4-triazoles and their use as pharmaceutically acceptable metal chelators ��˹��ŵ�� 2004-04-21 CN disclosed
CN-1223579-A Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators NOVARTIS AG (CH) 1999-07-21 CN disclosed
US-4254035-A BY REACTING GLYCINE AND AN AROMATIC ALDEHYDE IN THE PRESENCE OF ACETIC ANHYDRIDE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150252043-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES MPL, CSF3R, HGF HTR2C 3159/4885CHRNB4 4624/4885CHRNA3 4582/4885
US-20050197382-A1 Indolinone combinatorial libraries and related products and methods for the treatment of disease FRK, PTK2, DSTYK HTR2C 619/4885CHRNB4 4797/4885CHRNA3 4711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.