O-Xylene

O-Xylene

SCHEMBL4079935

Cc1ccccc1C.N=C=S.N=C=S

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.62
ACHE P22303 3/20 0.62
ALDH1A1 P00352 4/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 2/20 0.38
LMNA P02545 1/20 0.35
ALOX12 P18054 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
ESR1 P03372 1/20 0.35
TAAR1 Q96RJ0 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL27996449 1.00 TSHR (0.62) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL27930066 0.87 TSHR (0.71) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL7715827 0.87 TSHR (0.71) TSHRACHEALDH1A1CA1CA2
Isothiocyanate SCHEMBL330985 0.82 TRPA1 (0.46) TSHRACHEALDH1A1CA1CA2
O-Tolylamine SCHEMBL330781 0.82 CYP3A4 (0.68) TSHRACHEALDH1A1CYP3A4TDP1
Isothiocyanate SCHEMBL6156341 0.82 TSHR (0.41) TSHRACHEALDH1A1CA1CA2
Isothiocyanate SCHEMBL2886977 0.82 ALDH1A1 (0.71) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL163751 0.81 TSHR (0.62) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL29802653 0.81 TSHR (0.62) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL29860873 0.81 TSHR (0.62) TSHRACHEALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101614831-B High refractivity resin lens and preparation method thereof HANGZHOU XINSHUN CHEMICAL CO LTD 2010-10-27 CN claimed
CN-101786017-A Preparation method of solid-acid catalyst UNIV SHAOXING 2010-07-28 CN claimed
CN-101614831-A High refractivity resin lens and preparation method thereof HANGZHOU XINSHUN CHEMICAL CO L 2009-12-30 CN claimed
US-12552745-B2 Compound for optical materials, curable composition, cured body, and optical article TOKUYAMA CORPORATION (JP) 2026-02-17 US disclosed
EP-4679147-A1 MULTILAYER BODY, OPTICAL ARTICLE, COATING LAYER-CONTAINING MULTILAYER BODY, LENS, EYEGLASSES, AND FILM FOR WINDOWS TOKUYAMA CORPORATION (JP) 2026-01-14 EP disclosed
US-20250355282-A1 LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2025-11-20 US disclosed
US-20250257162-A1 CURABLE COMPOSITION, CURED BODY, LAMINATE, OPTICAL ARTICLE, LENS, AND EYEGLASSES TOKUYAMA CORPORATION (JP) 2025-08-14 US disclosed
EP-4560367-A1 LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2025-05-28 EP disclosed
EP-4516823-A1 CURABLE COMPOSITION, CURED BODY, LAMINATE, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2025-03-05 EP disclosed
CN-119072504-A Curable composition, cured product, laminate, optical article, lens, and glasses 株式会社德山 2024-12-03 CN disclosed
WO-2024080103-A1 OPTICAL MATERIAL COMPOSITION, CURED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES 株式会社トクヤマ 2024-04-18 WO disclosed
WO-2008014561-A1 BIOCOMPATIBLE POLYMER COMPOSITIONS POLYNOVO BIOMATERIALS PTY LTD (AU) 2008-02-07 WO disclosed
WO-2004011506-A1 A HIGH REFRACTIVE INDEX POLYMERIZABLE COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 2004-02-05 WO disclosed
EP-1265938-A1 OPTICAL RESIN COMPOSITION PPG Industries Ohio, Inc. (US) 2002-12-18 EP disclosed
EP-1250370-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG Industries Ohio, Inc. (US) 2002-10-23 EP disclosed
EP-1250369-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG Industries Ohio, Inc. (US) 2002-10-23 EP disclosed
WO-2001036506-A1 OPTICAL RESIN COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed
WO-2001036507-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed
WO-2001036508-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed
US-5622826-A COUPLING WITH AN ISOCYANATE OR ISOTHIOCYANATE HOUSTON ADVANCED RESEARCH CENTER (US) 1997-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552745-B2 Compound for optical materials, curable composition, cured body, and optical article C5, SCO2, ZYX TSHR 3533/4885ACHE 1259/4885ALDH1A1 1308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.