Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 5/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | TET3 | O43151 | 1/20 | 0.30 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4087831 | 0.88 | EPHX2 (0.38) | TET2STING1CYP2D6HDAC3HDAC1 | |
| SCHEMBL6380324 | 0.83 | STING1 (0.35) | STING1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL18290180 | 0.83 | STING1 (0.36) | TET2STING1CYP2D6HDAC3HDAC1 | |
| SCHEMBL4084580 | 0.82 | TET2 (0.37) | TET2 | |
| SCHEMBL644646 | 0.82 | TSHR (0.45) | STING1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL20851059 | 0.82 | STING1 (0.34) | STING1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL4838871 | 0.81 | TET2 (0.42) | TET2CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL23161369 | 0.80 | TSHR (0.39) | TET2STING1CYP2D6HDAC3HDAC1 | |
| SCHEMBL28815438 | 0.78 | STING1 (0.36) | STING1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL9218327 | 0.78 | HDAC3 (0.35) | TET2HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841380-B1 | Method of making polymeric binders and use thereof in antifouling paints | WITCO GMBH (DE) | 1999-08-25 | — | — | EP | claimed |
| EP-0841380-A1 | Method of making polymeric binders and use thereof in antifouling paints | Witco GmbH (DE) | 1998-05-13 | — | — | EP | claimed |
| EP-4058435-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | Genentech, Inc. (US) | 2022-09-21 | — | — | EP | disclosed |
| US-20220281819-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2022-09-08 | — | — | US | disclosed |
| CN-114728905-A | Therapeutic compounds and methods of use | 基因泰克公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021097110-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2021-05-20 | — | — | WO | disclosed |
| WO-2021097110-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2021-05-20 | — | — | WO | disclosed |
| US-7494759-B2 | Positive resist compositions and process for the formation of resist patterns with the same | TOKYO OHKA KOGYO CO., LTD. (JP) | 2009-02-24 | — | — | US | disclosed |
| US-20080070998-A1 | Foam Production Method | OJI PAPER CO., LTD. (JP) | 2008-03-20 | — | — | US | disclosed |
| US-20070224538-A1 | Positive Resist Compositions and Process for the Formation of Resist Patterns With the Same | TOKYO OHKA KOGYO CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| EP-1795553-A1 | PROCESS FOR PRODUCING FOAM | Oji Paper Co., Ltd. (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-20030225230-A1 | Polymers for antifouling coatings and a process for the preparation thereof | JOTUN A/S | 2003-12-04 | — | — | US | disclosed |
| EP-0841380-B1 | Method of making polymeric binders and use thereof in antifouling paints | WITCO GMBH (DE) | 1999-08-25 | — | — | EP | disclosed |
| EP-0841380-A1 | Method of making polymeric binders and use thereof in antifouling paints | Witco GmbH (DE) | 1998-05-13 | — | — | EP | disclosed |
| EP-0833870-A1 | POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF | Jotun A/S (NO) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996041842-A1 | POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF | JOTUN A/S (NO) | 1996-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281819-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | VHL, NQO1, PCSK9 | TET2 652/4885STING1 2192/4885CYP2D6 1124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.