Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079989 | 0.78 | TET2 (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4202803 | 0.77 | TSHR (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8546872 | 0.75 | MAPT (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4087831 | 0.75 | EPHX2 (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL23768567 | 0.74 | CYP2C9 (0.40) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL882496 | 0.74 | TDP1 (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8546618 | 0.74 | HSD17B10 (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL11123745 | 0.73 | HSD17B10 (0.52) | TET2CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL22145756 | 0.73 | HDAC3 (0.36) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4838871 | 0.72 | TET2 (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457172-A | An alkoxycarbonylalkylthio(or sulfone or sulfoxide) alkyl acrylate monomer; homo- and copolymers; molding materials; castings; binders; coating vehicles | ELF ATOCHEM S.A. (FR) | 1995-10-10 | — | — | US | claimed |
| JP-6080624-A | — | — | None | — | — | JP | disclosed |
| JP-H0680624-A | NEW (META)ACRYLIC COMPOUND, ITS PREPARATION AND ITS APPLICATION TO SYNTHESIS OF NEW POLYMER | ELF ATOCHEM SA | 1994-03-22 | — | — | JP | disclosed |