Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397313 | 0.90 | HIF1A (0.47) | SERPINE1MAPTTP53THRBSMN1; SMN2 | |
| SCHEMBL4078804 | 0.90 | MAPT (0.47) | SERPINE1MAPTTP53THRBSMN1; SMN2 | |
| SCHEMBL4069651 | 0.89 | SERPINE1 (0.52) | SERPINE1MAPTTP53PTGDR2FFAR4 | |
| SCHEMBL3958851 | 0.88 | SERPINE1 (0.51) | SERPINE1MAPTTP53THRBSMN1; SMN2 | |
| SCHEMBL4392130 | 0.88 | SERPINE1 (0.47) | SERPINE1MAPTTP53THRBSMN1; SMN2 | |
| SCHEMBL4069649 | 0.82 | SERPINE1 (0.56) | SERPINE1MAPTTP53PTGDR2FFAR4 | |
| SCHEMBL4077970 | 0.80 | SERPINE1 (0.42) | SERPINE1MAPTPTGDR2FFAR4HDAC3 | |
| SCHEMBL4072264 | 0.79 | EDNRB (0.46) | SERPINE1MAPTSMN1; SMN2NPSR1HTT | |
| SCHEMBL4133133 | 0.79 | HIF1A (0.53) | MAPTTP53THRBSMN1; SMN2NPSR1 | |
| SCHEMBL4070333 | 0.78 | FABP1 (0.45) | SERPINE1ALDH1A1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |