Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.54 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.54 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096602 | 0.82 | NOS3 (0.60) | LTA4HHRH3PTGS2PTGS1ACHE | |
| SCHEMBL5998450 | 0.78 | HRH3 (0.55) | LTA4HHRH3PTGS2PTGS1ACHE | |
| SCHEMBL265809 | 0.78 | LTA4H (0.55) | LTA4HHRH3PTGS2PTGS1PRKAB2 | |
| SCHEMBL22838451 | 0.76 | LTA4H (0.56) | LTA4HHRH3PTGS2PTGS1PRKAB2 | |
| SCHEMBL28997664 | 0.75 | LTA4H (0.55) | LTA4HHRH3PTGS2PTGS1ACHE | |
| SCHEMBL56495 | 0.75 | LTA4H (0.90) | LTA4HHRH3PTGS2PTGS1PSMB1 | |
| SCHEMBL23724061 | 0.74 | LTA4H (0.87) | LTA4HHRH3PTGS2PTGS1PSMB1 | |
| Hydrochloric Acid SCHEMBL15254264 | 0.74 | LTA4H (0.87) | LTA4HHRH3PTGS2PTGS1PSMB1 | |
| SCHEMBL3937460 | 0.74 | LTA4H (0.87) | LTA4HHRH3PTGS2PTGS1PSMB1 | |
| SCHEMBL30488017 | 0.73 | ACHE (0.58) | LTA4HHRH3ACHEMAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046416-A1 | ANILINOPYRIMIDINES AS JAK KINASE INHIBITORS | TARGEGEN INC. (US) | 2009-04-09 | — | — | WO | claimed |