Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | SCN1A | P35498 | 3/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116849 | 0.82 | HTR2A (0.33) | SMN1; SMN2KMT2AMEN1HTR2ATAAR1 | |
| SCHEMBL4085556 | 0.80 | HTR2A (0.32) | SMN1; SMN2KMT2AMEN1HTR2ATAAR1 | |
| SCHEMBL4080545 | 0.80 | HTR2A (0.32) | SMN1; SMN2KMT2AMEN1HTR2ATAAR1 | |
| SCHEMBL4775948 | 0.80 | TRPA1 (0.47) | TRPA1SMN1; SMN2KMT2AMEN1HTR2A | |
| SCHEMBL9165581 | 0.80 | L3MBTL1 (0.43) | SMN1; SMN2KMT2AMEN1HTR2ACYP2D6 | |
| SCHEMBL8536881 | 0.80 | L3MBTL1 (0.43) | SMN1; SMN2KMT2AMEN1HTR2ACYP2D6 | |
| SCHEMBL9165582 | 0.80 | L3MBTL1 (0.43) | SMN1; SMN2KMT2AMEN1HTR2ACYP2D6 | |
| SCHEMBL2673956 | 0.80 | SLC6A2 (0.45) | SMN1; SMN2KMT2AMEN1CYP2D6CYP1A2 | |
| SCHEMBL28938736 | 0.77 | ALDH1A1 (0.39) | TRPA1SMN1; SMN2HTR2ACYP2D6SCN1A | |
| SCHEMBL4602744 | 0.77 | NPSR1 (0.40) | SMN1; SMN2KMT2AMEN1TAAR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170131-A1 | Agents for Imaging Apoptosis | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2009-07-02 | — | — | US | claimed |
| WO-2007134127-A2 | AGENTS FOR IMAGING APOPTOSIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-11-22 | — | — | WO | claimed |
| US-20090170131-A1 | Agents for Imaging Apoptosis | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2009-07-02 | — | — | US | disclosed |
| WO-2007134127-A3 | AGENTS FOR IMAGING APOPTOSIS | UNIV TEXAS (US) | 2008-01-17 | — | — | WO | disclosed |
| WO-2007134127-A2 | AGENTS FOR IMAGING APOPTOSIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007134127-A2 | AGENTS FOR IMAGING APOPTOSIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-11-22 | — | — | WO | disclosed |