Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271159 | 0.84 | NPC1 (0.41) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL8160722 | 0.80 | PNMT (0.49) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL1985362 | 0.77 | PNMT (0.49) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL524602 | 0.74 | PNMT (0.63) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL30103334 | 0.74 | PNMT (0.63) | NPC1RAB9APNMTHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL540142 | 0.74 | PNMT (0.53) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL8469127 | 0.73 | NPC1 (0.36) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL27885618 | 0.73 | PNMT (0.57) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL2877998 | 0.72 | PNMT (0.61) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL8154235 | 0.72 | PNMT (0.45) | NPC1RAB9APNMTHTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048170-A2 | Second catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | Sumitomo Chemical Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |