Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4080863 | 0.91 | PHF8 (0.50) | TSHRKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL28231911 | 0.81 | — | — | |
| Succinic Acid SCHEMBL28234642 | 0.72 | LMNA (0.46) | TSHRKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL14266652 | 0.67 | — | — | |
| SCHEMBL25244762 | 0.65 | — | — | |
| SCHEMBL9851254 | 0.65 | ALDH1A1 (0.32) | TSHRALDH1A1LMNA | |
| SCHEMBL16599483 | 0.63 | EGLN1 (0.54) | TSHRKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL4526050 | 0.63 | TSHR (0.65) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL12099109 | 0.63 | EGLN1 (0.54) | TSHRKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL11169173 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485697-B2 | Soluble rage protein | JAPAN AS REPRESENTED BY PRESIDENT OF KANAZAWA UNIVERSITY (JP) | 2009-02-03 | — | — | US | disclosed |
| EP-1380593-B1 | SOLUBLE RAGE PROTEIN | JAPAN GOVERNMENT (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20050033017-A1 | Soluble rage protein | JAPAN AS REPRESENTED BY PRESIDENT OF KANAZAWA UNIVERSITY (JP) | 2005-02-10 | — | — | US | disclosed |
| EP-1380593-A1 | SOLUBLE RAGE PROTEIN | Japan as represented by President of Kanazawa University (JP) | 2004-01-14 | — | — | EP | disclosed |