Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.50 |
| ▸ | KDM5C | P41229 | 3/20 | 0.50 |
| ▸ | KDM6B | O15054 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4080862 | 0.91 | TSHR (0.41) | PHF8KDM2AEGLN1KDM5CKDM6B | |
| Succinic Acid SCHEMBL28234642 | 0.84 | LMNA (0.46) | PHF8KDM2AEGLN1KDM5CKDM6B | |
| SCHEMBL16599483 | 0.76 | EGLN1 (0.54) | PHF8KDM2AEGLN1KDM5CKDM6B | |
| SCHEMBL12099109 | 0.76 | EGLN1 (0.54) | PHF8KDM2AEGLN1KDM5CKDM6B | |
| Acetone SCHEMBL12471567 | 0.70 | LMNA (0.52) | PHF8KDM2AEGLN1KDM5CKDM6B | |
| SCHEMBL28573004 | 0.70 | EGLN1 (0.46) | PHF8KDM2AEGLN1KDM5CKDM6B | |
| SCHEMBL1396840 | 0.69 | EGLN1 (0.50) | PHF8KDM2AEGLN1KDM5CKDM6B | |
| SCHEMBL17654221 | 0.69 | EGLN1 (0.50) | PHF8KDM2AEGLN1KDM5CKDM6B | |
| Succinic Acid SCHEMBL2148509 | 0.68 | EGLN1 (0.75) | PHF8KDM2AEGLN1KDM5CKDM6B | |
| Succinic Acid SCHEMBL16415716 | 0.68 | EGLN1 (0.75) | PHF8KDM2AEGLN1KDM5CKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485697-B2 | Soluble rage protein | JAPAN AS REPRESENTED BY PRESIDENT OF KANAZAWA UNIVERSITY (JP) | 2009-02-03 | — | — | US | disclosed |
| EP-1380593-B1 | SOLUBLE RAGE PROTEIN | JAPAN GOVERNMENT (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20050033017-A1 | Soluble rage protein | JAPAN AS REPRESENTED BY PRESIDENT OF KANAZAWA UNIVERSITY (JP) | 2005-02-10 | — | — | US | disclosed |
| EP-1380593-A1 | SOLUBLE RAGE PROTEIN | Japan as represented by President of Kanazawa University (JP) | 2004-01-14 | — | — | EP | disclosed |