Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PRKCA | P17252 | 3/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24228101 | 1.00 | LMNA (0.56) | LMNAALDH1A1MAPTPRKCAPRKCE | |
| SCHEMBL14075730 | 0.94 | MAPT (0.51) | LMNAALDH1A1MAPTPRKCAPRKCE | |
| SCHEMBL13189289 | 0.94 | MAPT (0.51) | LMNAALDH1A1MAPTPRKCAPRKCE | |
| SCHEMBL2279093 | 0.90 | MAPT (0.58) | LMNAALDH1A1MAPTPRKCAPRKCE | |
| SCHEMBL9717446 | 0.88 | ALDH1A1 (0.75) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL18125055 | 0.88 | ALDH1A1 (0.75) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL14553744 | 0.87 | LMNA (0.72) | LMNAALDH1A1MAPTPRKCAPRKCE | |
| SCHEMBL8394438 | 0.87 | LMNA (0.72) | LMNAALDH1A1MAPTPRKCAPRKCE | |
| SCHEMBL5682256 | 0.87 | LMNA (0.72) | LMNAALDH1A1MAPTPRKCAPRKCE | |
| SCHEMBL16584788 | 0.87 | LMNA (0.72) | LMNAALDH1A1MAPTPRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210244651-A1 | ANTI-WRINKLE COSMETIC COMPOSITION | NAL PHARMACEUTICAL GROUP LIMITED (HK) | 2021-08-12 | — | — | US | claimed |
| WO-2020030991-A1 | DOSAGE FORM FOR INSERTION INTO THE MOUTH | NAL PHARMACEUTICAL GROUP LIMITED (CN) | 2020-02-13 | — | — | WO | claimed |
| WO-2019135125-A1 | SEMI-SOLID DOSAGE FORM FOR TOPICAL APPLICATION | NAL PHARMACEUTICAL GROUP LIMITED (CN) | 2019-07-11 | — | — | WO | claimed |
| WO-2008097953-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING SUBSTITUTED INDOLE ACID DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | WYETH (US) | 2008-08-14 | — | — | WO | claimed |
| US-20080188540-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SUBSTITUTED INDOLE ACID DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | WYETH (US) | 2008-08-07 | — | — | US | claimed |
| US-20210244651-A1 | ANTI-WRINKLE COSMETIC COMPOSITION | NAL PHARMACEUTICAL GROUP LIMITED (HK) | 2021-08-12 | — | — | US | disclosed |
| WO-2020030991-A1 | DOSAGE FORM FOR INSERTION INTO THE MOUTH | NAL PHARMACEUTICAL GROUP LIMITED (CN) | 2020-02-13 | — | — | WO | disclosed |
| WO-2019135123-A1 | LIQUID DOSAGE FORM FOR TOPICAL APPLICATION | NAL PHARMACEUTICAL GROUP LIMITED (CN) | 2019-07-11 | — | — | WO | disclosed |
| US-20100236713-A1 | FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY | KONICA MINOLTA OPTO, INC. (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20090185112-A1 | POLARIZING PLATE PROTECTIVE FILM AND METHOD FOR MANUFACTURING THE SAME, POLARIZING PLATE AND METHOD FOR MANUFACTURING THE SAME, AND LIQUID CRYSTAL DISPLAY DEVICE | KONICA MINOLTA OPTO, INC. (JP) | 2009-07-23 | — | — | US | disclosed |
| US-20090185112-A1 | POLARIZING PLATE PROTECTIVE FILM AND METHOD FOR MANUFACTURING THE SAME, POLARIZING PLATE AND METHOD FOR MANUFACTURING THE SAME, AND LIQUID CRYSTAL DISPLAY DEVICE | KONICA MINOLTA OPTO, INC. (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-2061757-A2 | NOVEL INDOLE POLYMORPHS | Wyeth (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20080213512-A1 | Method for manufacturing cellulose ester film, and cellulose ester film, optical film, polarizing plate and liquid crystal display device using the same | KONICA MINOLTA OPTO, INC. (JP) | 2008-09-04 | — | — | US | disclosed |
| WO-2008097938-A2 | INDOLE POLYMORPHS | WYETH (US) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008097953-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING SUBSTITUTED INDOLE ACID DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | WYETH (US) | 2008-08-14 | — | — | WO | disclosed |
| US-20080188540-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SUBSTITUTED INDOLE ACID DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | WYETH (US) | 2008-08-07 | — | — | US | disclosed |
| US-20080188542-A1 | NOVEL INDOLE POLYMORPHS | WYETH (US) | 2008-08-07 | — | — | US | disclosed |
| US-20070227652-A1 | FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY | KONICA MINOLTA OPTO, INC. (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070227652-A1 | FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY | KONICA MINOLTA OPTO, INC. (JP) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188542-A1 | NOVEL INDOLE POLYMORPHS | CYP3A43, IDO1, CYP3A4 | LMNA 3611/4885ALDH1A1 241/4885MAPT 84/4885 |
| US-20080188540-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SUBSTITUTED INDOLE ACID DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | SERPINE1, TFPI, MMP1 | LMNA 1226/4885ALDH1A1 789/4885MAPT 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.