Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.54 |
| ▸ | HINT1 | P49773 | 1/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | KRAS | P01116 | 4/20 | 0.51 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861503 | 1.00 | NT5E (0.60) | NT5ETGM2IMPDH2HINT1STING1 | |
| Guanosine SCHEMBL2447866 | 0.93 | NT5E (0.62) | NT5ETGM2IMPDH2HINT1KRAS | |
| SCHEMBL9124928 | 0.92 | NT5E (0.53) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL407394 | 0.90 | NT5E (0.59) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL1527362 | 0.90 | NT5E (0.59) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL19183426 | 0.88 | NT5E (0.57) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL22636005 | 0.87 | NT5E (0.62) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL22498538 | 0.87 | NT5E (0.62) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL4651242 | 0.87 | NT5E (0.56) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL30867115 | 0.87 | NT5E (0.53) | NT5ETGM2IMPDH2HINT1STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7575901-B2 | Propagating escherichia mutant which produces 5'-inosinic acid or 5'-guanylic acid; identifying nucleotidase gene associated with generating nucleoside 5'-phosphate esters | AJINOMOTO CO., INC. (JP) | 2009-08-18 | — | — | US | claimed |
| US-20080026428-A1 | METHOD FOR PRODUCING NUCLEOTIDE BY FERMENTATION | AJINOMOTO CO., INC. (JP) | 2008-01-31 | — | — | US | claimed |
| WO-2022266027-A1 | PREVENTION AND TREATMENT OF POST-INFECTION NEUROLOGICAL DISORDERS AND CLOTTING/THROMBOTIC DISORDERS | BARANOWITZ STEVEN (US) | 2022-12-22 | — | — | WO | disclosed |
| EP-3641566-A1 | METHODS FOR INCREASING GROWTH OF BENEFICIAL BACTERIA IN THE GASTROINTESTINAL TRACT | Abbott Laboratories (US) | 2020-04-29 | — | — | EP | disclosed |
| WO-2018237149-A1 | METHODS FOR INCREASING GROWTH OF BENEFICIAL BACTERIA IN THE GASTROINTESTINAL TRACT | ABBOTT LABORATORIES (US) | 2018-12-27 | — | — | WO | disclosed |
| US-20120184503-A1 | NUTRITIONAL COMPOSITIONS COMPRISING HUMAN MILK OLIGOSACCHARIDES AND NUCLEOTIDES AND USES THEREOF FOR TREATING AND/OR PREVENTING ENTERIC VIRAL INFECTION | ABBOTT LABORATORIES (US) | 2012-07-19 | — | — | US | disclosed |