Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.54 |
| ▸ | HINT1 | P49773 | 1/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | KRAS | P01116 | 4/20 | 0.51 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081026 | 1.00 | NT5E (0.60) | NT5ETGM2IMPDH2HINT1STING1 | |
| Guanosine SCHEMBL2447866 | 0.93 | NT5E (0.62) | NT5ETGM2IMPDH2HINT1KRAS | |
| SCHEMBL9124928 | 0.92 | NT5E (0.53) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL407394 | 0.90 | NT5E (0.59) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL1527362 | 0.90 | NT5E (0.59) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL19183426 | 0.88 | NT5E (0.57) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL22636005 | 0.87 | NT5E (0.62) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL22498538 | 0.87 | NT5E (0.62) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL4651242 | 0.87 | NT5E (0.56) | NT5ETGM2IMPDH2HINT1STING1 | |
| SCHEMBL30867115 | 0.87 | NT5E (0.53) | NT5ETGM2IMPDH2HINT1STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122572-B2 | For use in Hydrogen Bonding Liquid Chromatography, environmental remediation by removal of undesired ions or neutral molecules, removal of phosphate for kidney dialysis, drug delivery, separation | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2006-10-17 | — | — | US | disclosed |
| US-7041819-B2 | Halogenated calixpyrroles and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-05-09 | — | — | US | disclosed |
| US-6984734-B2 | Cyclo[n]pyrroles and methods thereto | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-01-10 | — | — | US | disclosed |
| US-20030229131-A1 | Cyclo[n]pyrroles and methods thereto | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2003-12-11 | — | — | US | disclosed |
| WO-2003072581-A1 | CYCLO[N]PYRROLES AND METHODS THERETO | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2003-09-04 | — | — | WO | disclosed |
| WO-2003018548-A2 | HALOGENATED CALIXPYRROLES, CALIXPYRIDINOPYRROLES AND CALIXPYRIDINES, AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2003-03-06 | — | — | WO | disclosed |
| US-20020115566-A1 | Halogenated calixpyrroles, calixpyridinopyrroles and calixpyridines, and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-08-22 | — | — | US | disclosed |
| US-20020026047-A1 | Calixpyrroles, calixpyridinopyrroles, and calixpyridines | BOARD OF REGENTS, THE | 2002-02-28 | — | — | US | disclosed |
| US-6262257-B1 | SELECTIVE ION- AND NEUTRAL MOLECULE-BINDING AGENTS FORMING SUPRAMOLECULAR ENSEMBLES, AND ION- AND NEUTRAL MOLECULE-SEPARATION AGENTS | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM | 2001-07-17 | — | — | US | disclosed |
| EP-0891364-A1 | CALIXPYRROLES, CALIXPYRIDINOPYRROLES AND CALIXPYRIDINES | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5808059-A | CHROMATOGRAPHY; ELECTROPHORESIS | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 1998-09-15 | — | — | US | disclosed |
| US-5744302-A | USING A PORPHYRIN; COMPLEXING | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-04-28 | — | — | US | disclosed |
| WO-1997037995-A1 | CALIXPYRROLES, CALIXPYRIDINOPYRROLES AND CALIXPYRIDINES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1997-10-16 | — | — | WO | disclosed |
| US-5672490-A | PROMOTING THE SPLITTING DNA BY MIXING WITH A SAPPHYRIN-EDTA CONJUGATE COMPOUND | THE UNIVERSITY OF TEXAS BOARD OF REGENTS (US) | 1997-09-30 | — | — | US | disclosed |
| US-5530123-A | ANTIVIRAL AND CHEMOTHERAPEUTICAL AGENT FOR CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-06-25 | — | — | US | disclosed |
| US-5457195-A | Sapphyrin derivatives and conjugates | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229131-A1 | Cyclo[n]pyrroles and methods thereto | PPOX, QPCT, PPIE | NT5E 706/4885TGM2 3279/4885IMPDH2 1607/4885 |
| US-20020115566-A1 | Halogenated calixpyrroles, calixpyridinopyrroles and calixpyridines, and uses thereof | CALD1, CALU, CLASP1 | NT5E 3680/4885TGM2 3797/4885IMPDH2 3386/4885 |
| US-20020026047-A1 | Calixpyrroles, calixpyridinopyrroles, and calixpyridines | CALD1, DAP3, CALR | NT5E 3281/4885TGM2 2752/4885IMPDH2 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.