Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | HINT1 | P49773 | 1/20 | 0.50 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 5/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19183426 | 0.90 | NT5E (0.57) | NT5ETGM2HINT1FUT5IMPDH2 | |
| SCHEMBL4081026 | 0.87 | NT5E (0.60) | NT5ETGM2HINT1FUT5IMPDH2 | |
| SCHEMBL5861503 | 0.87 | NT5E (0.60) | NT5ETGM2HINT1FUT5IMPDH2 | |
| SCHEMBL407394 | 0.86 | NT5E (0.59) | NT5ETGM2HINT1FUT5IMPDH2 | |
| SCHEMBL1527362 | 0.86 | NT5E (0.59) | NT5ETGM2HINT1FUT5IMPDH2 | |
| SCHEMBL309061 | 0.83 | TGM2 (0.55) | NT5ETGM2HINT1FUT5IMPDH2 | |
| SCHEMBL18955504 | 0.83 | TGM2 (0.54) | NT5ETGM2HINT1FUT5IMPDH2 | |
| SCHEMBL18640378 | 0.82 | NT5E (0.57) | NT5ETGM2HINT1FUT5IMPDH2 | |
| SCHEMBL22498538 | 0.82 | NT5E (0.62) | NT5ETGM2HINT1FUT5IMPDH2 | |
| SCHEMBL22636005 | 0.82 | NT5E (0.62) | NT5ETGM2HINT1FUT5IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844135-B1 | ESCHERICHIA STRAIN CAPABLE OF CONVERTING XMP TO GMP AND MAINTAINING THE INACTIVATED STATE OF GENE(S) ASSOCIATED WITH GMP DEGRADATION AND METHODS OF USING THE SAME | CJ CHEILJEDANG CORP (KR) | 2013-12-25 | — | — | EP | claimed |
| EP-1753774-B1 | 2\"-NITROBENZYL-MODIFIED RIBONUCLEOTIDES | ASM SCIENT INC (US) | 2008-09-10 | — | — | EP | claimed |
| WO-2000025830-A2 | BIOMIMETIC ELEMENTS CONTAINING IODINE AND/OR TELLURIUM, THE PRODUCTION THEREOF AND THEIR USE | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 2000-05-11 | — | — | WO | claimed |
| EP-0090417-B1 | PROCESS FOR PRODUCING 3'-DEOXYGUANOSINE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1989-03-01 | — | — | EP | claimed |
| WO-2000025830-A2 | BIOMIMETIC ELEMENTS CONTAINING IODINE AND/OR TELLURIUM, THE PRODUCTION THEREOF AND THEIR USE | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 2000-05-11 | — | — | WO | disclosed |
| EP-0721372-B1 | NUCLEOSIDE-CONTAINING SORBENT FOR AFFINITY CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 1997-09-03 | — | — | EP | disclosed |
| EP-0721372-A1 | NUCLEOTIDE-CONTAINING SORBENT FOR AFFINITY CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 1996-07-17 | — | — | EP | disclosed |
| WO-1995009694-A1 | NUCLEOTIDE-CONTAINING SORBENT FOR AFFINITY CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 1995-04-13 | — | — | WO | disclosed |