Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25407528 | 0.88 | ALDH1A1 (0.79) | ALDH1A1KMT2APOLBKDM4EHPSE | |
| SCHEMBL30388597 | 0.88 | ALDH1A1 (0.79) | ALDH1A1KMT2APOLBKDM4EHPSE | |
| SCHEMBL27789682 | 0.88 | ALDH1A1 (0.77) | ALDH1A1KMT2AKDM4EPARP10RXRA | |
| SCHEMBL29875598 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KMT2AKDM4ETDP1 | |
| SCHEMBL28365983 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KMT2APOLBKDM4EPARP10 | |
| SCHEMBL5121870 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KMT2APOLBKDM4EPARP10 | |
| SCHEMBL1316975 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KMT2AKDM4EMCL1TDP1 | |
| SCHEMBL539134 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KMT2AKDM4ETDP1 | |
| SCHEMBL711082 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KMT2APOLBKDM4EPARP10 | |
| SCHEMBL17908039 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KMT2APOLBKDM4EPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1538160-B1 | Substituted Isoquinolin-3-carboxyamides, their preparation and medical use | FIBROGEN INC (US) | 2009-06-03 | — | — | EP | disclosed |
| US-7393625-B2 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2008-07-01 | — | — | US | disclosed |
| EP-1840646-A1 | Photothermographic material | FUJIFILM Corporation (JP) | 2007-10-03 | — | — | EP | disclosed |
| US-20070224555-A1 | Photothermographic material | FUJIFILM CORPORATION | 2007-09-27 | — | — | US | disclosed |
| EP-0911340-B1 | Substituted Isoquinolin-3-Carboxyamides, their preparation and medical use | FIBROGEN INC (US) | 2005-07-06 | — | — | EP | disclosed |
| US-6093730-A | AN ENZYME INHIBITORS OF PROLYL-4-HYDROXYLASE FOR TREATING FIBROTIC DISORDERS AND INHIBITING COLLAGEN BIOSYNTHESIS | HOECHST MARION ROUSSEL DEUTSCHLAND GMBH (DE) | 2000-07-25 | — | — | US | disclosed |
| EP-0911340-A2 | Substituted Isoquinolin-3-Carboxyamides, their preparation and medical use | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-04-28 | — | — | EP | disclosed |