SCHEMBL1316975

SCHEMBL1316975

CC(C)Oc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.73
KMT2A Q03164 4/20 0.56
CSNK2A1 P68400 1/20 0.53
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
PTGS2 P35354 2/20 0.52
CA12 O43570 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
ALOX5 P09917 1/20 0.52
MCL1 Q07820 3/20 0.49
MEN1 O00255 3/20 0.48
KDM4E B2RXH2 3/20 0.48
HPGD P15428 3/20 0.48
HSD17B10 Q99714 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
KDR P35968 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7646688 0.87 ALDH1A1 (0.59) ALDH1A1KMT2ACA1CA2CA12
SCHEMBL9303744 0.87 ALDH1A1 (0.56) ALDH1A1KMT2AMCL1KDM4EHPGD
SCHEMBL9302989 0.87 ALDH1A1 (0.56) ALDH1A1KMT2AMCL1KDM4E
SCHEMBL539134 0.85 ALDH1A1 (0.73) ALDH1A1KMT2ACA1CA2CA12
SCHEMBL29875598 0.85 ALDH1A1 (0.73) ALDH1A1KMT2ACA1CA2CA12
SCHEMBL4081642 0.85 ALDH1A1 (1.00) ALDH1A1KMT2AMCL1KDM4ETDP1
SCHEMBL9678008 0.83 ALDH1A1 (0.53) ALDH1A1KMT2ACSNK2A1CA1CA2
SCHEMBL1316757 0.82 CA12 (0.61) ALDH1A1KMT2ACA1CA2PTGS2
SCHEMBL31364552 0.81 KDM4E (0.64) ALDH1A1KMT2ACSNK2A1CA1CA2
SCHEMBL344841 0.81 KDM4E (0.64) ALDH1A1KMT2ACSNK2A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 EP disclosed
CN-101648919-A 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof INST MATERIA MEDICA CAMS 2010-02-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 ALDH1A1 813/4885KMT2A 950/4885CSNK2A1 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.