SCHEMBL539134

SCHEMBL539134

CC(C)Oc1ccc(C(=O)O)c(O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.73
CA12 O43570 2/20 0.57
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA7 P43166 2/20 0.57
CA9 Q16790 2/20 0.57
CA14 Q9ULX7 2/20 0.57
TSHR P16473 1/20 0.57
KMT2A Q03164 2/20 0.56
HPGD P15428 4/20 0.53
CYP3A4 P08684 2/20 0.53
MAPK1 P28482 2/20 0.53
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
KDM4E B2RXH2 4/20 0.48
MAPT P10636 2/20 0.48
GAA P10253 1/20 0.48
ESR2 Q92731 1/20 0.48
PTPN1 P18031 1/20 0.48
MAOB P27338 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29875598 1.00 ALDH1A1 (0.73) ALDH1A1CA12CA1CA2CA7
SCHEMBL9002666 0.87 NPC1 (0.67) ALDH1A1CA12CA1CA2CA7
SCHEMBL6577473 0.87 ALDH1A1 (0.70) ALDH1A1CA12CA1CA2CA7
SCHEMBL9304985 0.87 ALDH1A1 (0.56) ALDH1A1CA12CA1CA2CA7
SCHEMBL9304482 0.87 PPARD (0.61) ALDH1A1KMT2AKDM4EMAOB
SCHEMBL9304314 0.87 PPARD (0.58) ALDH1A1KMT2AMAOB
SCHEMBL1316975 0.85 ALDH1A1 (0.73) ALDH1A1CA12CA1CA2CA7
SCHEMBL4081642 0.85 ALDH1A1 (1.00) ALDH1A1KMT2AKDM4ETDP1
SCHEMBL12316316 0.84 PARP10 (0.58) ALDH1A1CA12CA1CA2CA7
SCHEMBL5145623 0.83 ALDH1A1 (0.51) ALDH1A1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1636550-B Water-in-oil emulsion composition SHISEIDO CO LTD 2010-06-16 CN claimed
EP-3389595-B1 COMBINATION OF POLYION COMPLEX PARTICLE AND NON-POLYMERIC ACID HAVING TWO OR MORE ACID DISSOCIATION CONSTANTS OREAL (FR) 2025-11-05 EP disclosed
EP-3638192-B1 COMBINATION OF POLYION COMPLEX PARTICLE AND NON-POLYMERIC ACID OR BASE HAVING TWO OR MORE DISSOCIATION CONSTANTS OREAL (FR) 2025-04-02 EP disclosed
EP-3638201-B1 COMBINATION OF POLYION COMPLEX PARTICLE AND NON-POLYMERIC BASE HAVING TWO OR MORE DISSOCIATION CONSTANTS OREAL (FR) 2025-02-26 EP disclosed
WO-2024214568-A1 WATER-BASED COSMETIC 株式会社 資生堂 2024-10-17 WO disclosed
US-12029303-B2 Method for preparation of a cosmetic kit SHISEIDO COMPANY, LTD. (JP) 2024-07-09 US disclosed
WO-2024135300-A1 COSMETIC COMPOSITION, COSMETIC COMPOSITION FOR SUPPRESSING DISCOLORATION, AND DISCOLORATION SUPPRESSANT 株式会社資生堂 2024-06-27 WO disclosed
US-11975093-B2 Composition comprising oil and polyion complex including cellulose-based cationic polymer with at least one fatty chain L'OREAL (FR) 2024-05-07 US disclosed
WO-2024090247-A1 BEAUTY COMPOSITION, BEAUTY METHOD, AND AGENT FOR PROMOTING SKIN PERMEABILITY OF ALKOXY SALICYLIC ACID OR SALT THEREOF 株式会社 資生堂 2024-05-02 WO disclosed
EP-3597174-B1 TWO-COMPONENT COSMETIC SHISEIDO CO LTD (JP) 2024-04-17 EP disclosed
CN-101048133-A Skin preparation for external use SHISEIDO CO LTD (JP) 2007-10-03 CN disclosed
EP-1563831-A1 EXTERNAL COMPOSITION FOR SKIN Shiseido Co., Ltd. (JP) 2005-08-17 EP disclosed
CN-1636550-A Water-in-oil emulsion composition SHISEIDO CO LTD (JP) 2005-07-13 CN disclosed
CN-1636600-A Skin external preparation SHISEIDO CO LTD (JP) 2005-07-13 CN disclosed
CN-1636549-A Oil-in-water emulsion composition SHISEIDO CO LTD (JP) 2005-07-13 CN disclosed
EP-0570230-B1 External preparation for skin SHISEIDO CO LTD (JP) 1998-09-30 EP disclosed
US-5580549-A BLEACHING; 2-HYDROXYBENZOIC ACID COMPOUND SHISEIDO CO., LTD. (JP) 1996-12-03 US disclosed
EP-0711286-A1 BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY ITALFARMACO S.p.A. (IT) 1996-05-15 EP disclosed
WO-1995004048-A1 BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY ITALFARMACO S.P.A. (IT) 1995-02-09 WO disclosed
EP-0570230-A1 External preparation for skin SHISEIDO COMPANY LIMITED (JP) 1993-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11975093-B2 Composition comprising oil and polyion complex including cellulose-based cationic polymer with at least one fatty chain PRKCA, PRKCH, CUTA ALDH1A1 4493/4885CA12 629/4885CA1 1804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.