Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.52 |
| ▸ | MC4R | P32245 | 6/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | KISS1R | Q969F8 | 5/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSH | P09668 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957536 | 1.00 | GHSR (0.52) | GHSRMC4RNPBWR1KISS1RCTSL | |
| SCHEMBL4957456 | 0.99 | GHSR (0.53) | GHSRMC4RNPBWR1KISS1RCTSL | |
| SCHEMBL5519060 | 0.95 | GHSR (0.50) | GHSRMC4RNPBWR1KISS1RCTSL | |
| SCHEMBL6547133 | 0.95 | GHSR (0.51) | GHSRMC4RNPBWR1KISS1RCTSL | |
| SCHEMBL29531916 | 0.90 | GHSR (0.50) | GHSRMC4RNPBWR1KISS1RCTSL | |
| SCHEMBL21570979 | 0.90 | GHSR (0.64) | GHSRMC4RNPBWR1KISS1R | |
| SCHEMBL21570985 | 0.90 | GHSR (0.64) | GHSRMC4RNPBWR1KISS1R | |
| SCHEMBL21570983 | 0.90 | GHSR (0.64) | GHSRMC4RNPBWR1KISS1R | |
| SCHEMBL31001649 | 0.87 | GHSR (0.57) | GHSRMC4RKISS1R | |
| SCHEMBL29675015 | 0.87 | IL23R (0.52) | GHSRCTSLCTSHCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759772-B1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA INC (US) | 2004-01-21 | — | — | EP | claimed |
| EP-1545580-A4 | NEW THERAPEUTIC USES OF TRI-, TETRA-, PENTA-, AND POLYPEPTIDES | INNAPHARMA INC (US) | 2009-08-05 | — | — | EP | disclosed |
| US-20080176806-A1 | Therapeutic uses of tri-, tetra-, penta-, and polypeptides | INNAPHARMA, INC. | 2008-07-24 | — | — | US | disclosed |
| US-20080004224-A1 | DERMATOLOGICAL USES OF TRI-, TETRA-, PENTA-, AND POLYPEPTIDES | HLAVKA JOSEPH J | 2008-01-03 | — | — | US | disclosed |
| WO-2007137015-A2 | DERMATOLOGICAL USES OF TRI-, TETRA-, PENTA-, AND POLYPEPTIDES | TETRAGENEX PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| EP-1545580-A2 | NEW THERAPEUTIC USES OF TRI-, TETRA-, PENTA-, AND POLYPEPTIDES | Innapharma, Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| US-6767897-B2 | ADMINISTERING TO THE PATIENT AT LEAST ONE TETRAPEPTIDE OR SALT THEREOF FOR THERAPY OF PHYSIOLOGICAL, PSYCHOSOMATIC, NEUROLOGICAL OR PSYCHIATRIC DISORDER | INNAPHARMA, INC. | 2004-07-27 | — | — | US | disclosed |
| EP-0759772-B1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA INC (US) | 2004-01-21 | — | — | EP | disclosed |
| WO-2003087137-A2 | NEW THERAPEUTIC USES OF TRI-, TETRA-, PENTA-, AND POLYPEPTIDES | INNAPHARMA, INC. (US) | 2003-10-23 | — | — | WO | disclosed |
| US-20030176354-A1 | Therapeutic uses of tri-, tetra-, penta-, and polypeptides | TETRAGENEX PHARMACEUTICALS, INC. | 2003-09-18 | — | — | US | disclosed |
| WO-1999022758-A1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA, INC. (US) | 1999-05-14 | — | — | WO | disclosed |
| EP-0759772-A4 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA INC (US) | 1999-04-21 | — | — | EP | disclosed |
| US-5767083-A | INHIBITION OF MELANOCYTE STIMULATTING HORMONE | INNAPHARMA, INC. (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0759772-A1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995030430-A1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA, INC. (US) | 1995-11-16 | — | — | WO | disclosed |