Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.64 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.50 |
| ▸ | PRKACB | P22694 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21570979 | 1.00 | GHSR (0.64) | GHSRKISS1RPRKACBNPBWR1MC4R | |
| SCHEMBL21570983 | 1.00 | GHSR (0.64) | GHSRKISS1RPRKACBNPBWR1MC4R | |
| SCHEMBL30866241 | 0.94 | GHSR (0.62) | GHSRKISS1RPRKACBNPBWR1 | |
| SCHEMBL30866229 | 0.92 | GHSR (0.67) | GHSRKISS1R | |
| SCHEMBL31026132 | 0.91 | GHSR (0.63) | GHSRKISS1RNPBWR1 | |
| SCHEMBL31001649 | 0.90 | GHSR (0.57) | GHSRKISS1RMC4R | |
| SCHEMBL30866204 | 0.90 | GHSR (0.63) | GHSRKISS1RNPBWR1TACR1 | |
| SCHEMBL4082307 | 0.90 | GHSR (0.52) | GHSRKISS1RNPBWR1MC4R | |
| SCHEMBL4957536 | 0.90 | GHSR (0.52) | GHSRKISS1RNPBWR1MC4R | |
| SCHEMBL31026129 | 0.89 | GHSR (0.60) | GHSRKISS1RNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260085093-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2026-03-26 | — | — | US | disclosed |
| US-20260078147-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2026-03-19 | — | — | US | disclosed |
| US-12479887-B2 | Inhibitors for protein n-terminal methyltransferase and uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2025-11-25 | — | — | US | disclosed |
| US-20190352338-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085093-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | GNMT, PRMT5, INMT | GHSR 2176/4885KISS1R 4855/4885PRKACB 1012/4885 |
| US-12479887-B2 | Inhibitors for protein n-terminal methyltransferase and uses thereof | GNMT, PRMT1, PRMT5 | GHSR 3711/4885KISS1R 4832/4885PRKACB 927/4885 |
| US-20260078147-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | SMYD2, INMT, PRMT6 | GHSR 3480/4885KISS1R 4679/4885PRKACB 2608/4885 |
| US-20190352338-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | GNMT, PRMT1, PRMT5 | GHSR 3711/4885KISS1R 4832/4885PRKACB 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.