Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.51 |
| ▸ | MC4R | P32245 | 5/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | MC1R | Q01726 | 2/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.44 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSH | P09668 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957456 | 0.96 | GHSR (0.53) | GHSRMC4RNPBWR1KISS1RCTSL | |
| SCHEMBL4957536 | 0.95 | GHSR (0.52) | GHSRMC4RNPBWR1KISS1RCTSL | |
| SCHEMBL4082307 | 0.95 | GHSR (0.52) | GHSRMC4RNPBWR1KISS1RCTSL | |
| SCHEMBL5519060 | 0.94 | GHSR (0.50) | GHSRMC4RNPBWR1CXCR4KISS1R | |
| SCHEMBL29531916 | 0.91 | GHSR (0.50) | GHSRMC4RNPBWR1CXCR4KISS1R | |
| SCHEMBL31001649 | 0.88 | GHSR (0.57) | GHSRMC4RKISS1R | |
| SCHEMBL29674951 | 0.88 | IL23R (0.52) | GHSRCXCR4IL23RCTSLCTSS | |
| SCHEMBL29675015 | 0.88 | IL23R (0.52) | GHSRCXCR4IL23RCTSLCTSS | |
| SCHEMBL30752452 | 0.87 | KISS1R (0.53) | GHSRNPBWR1CXCR4KISS1R | |
| SCHEMBL2195535 | 0.86 | GHSR (0.53) | GHSRMC4RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759772-B1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA INC (US) | 2004-01-21 | — | — | EP | claimed |